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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDPK1
All Species:
25.45
Human Site:
Y146
Identified Species:
46.67
UniProt:
O15530
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15530
NP_002604.1
556
63152
Y146
H
P
F
F
V
K
L
Y
F
T
F
Q
D
D
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537000
560
63701
Y150
H
P
F
F
V
K
L
Y
F
T
F
Q
D
D
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2A0
559
63740
Y149
H
P
F
F
V
K
L
Y
F
T
F
Q
D
D
E
Rat
Rattus norvegicus
O55173
559
63591
Y149
H
P
F
F
V
K
L
Y
F
T
F
Q
D
D
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518589
320
36424
Chicken
Gallus gallus
Q6U1I9
432
48872
S79
A
N
P
S
P
P
P
S
P
S
Q
Q
I
N
L
Frog
Xenopus laevis
Q6GPN6
434
49096
S81
E
N
S
S
P
P
P
S
P
S
Q
Q
I
N
L
Zebra Danio
Brachydanio rerio
Q7ZTW4
433
48964
S80
S
N
P
S
P
P
P
S
P
S
Q
Q
I
N
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W0V1
836
94060
S311
V
P
G
F
V
N
L
S
C
T
F
Q
D
Q
R
Honey Bee
Apis mellifera
XP_394208
537
61368
E146
K
V
G
S
F
D
I
E
C
T
K
F
Y
S
A
Nematode Worm
Caenorhab. elegans
Q9Y1J3
636
71898
Y138
H
P
F
V
T
Q
L
Y
T
H
F
H
D
Q
A
Sea Urchin
Strong. purpuratus
XP_786576
539
61612
Y148
H
P
F
F
V
R
L
Y
F
T
F
Q
D
N
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12236
1081
121642
F244
S
P
S
V
V
R
L
F
S
T
F
Q
D
E
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
93.3
N.A.
94.8
95.3
N.A.
52.1
28.6
28
27.5
N.A.
32.5
54.1
32.5
58
Protein Similarity:
100
N.A.
N.A.
95
N.A.
96.2
96.4
N.A.
54.6
44
43.8
43.3
N.A.
44.1
66.1
52.2
70.3
P-Site Identity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
0
6.6
6.6
6.6
N.A.
53.3
6.6
46.6
80
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
0
20
20
20
N.A.
53.3
13.3
53.3
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
35.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
16
% A
% Cys:
0
0
0
0
0
0
0
0
16
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
8
0
0
0
0
0
0
62
31
0
% D
% Glu:
8
0
0
0
0
0
0
8
0
0
0
0
0
8
31
% E
% Phe:
0
0
47
47
8
0
0
8
39
0
62
8
0
0
0
% F
% Gly:
0
0
16
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
47
0
0
0
0
0
0
0
0
8
0
8
0
0
0
% H
% Ile:
0
0
0
0
0
0
8
0
0
0
0
0
24
0
0
% I
% Lys:
8
0
0
0
0
31
0
0
0
0
8
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
62
0
0
0
0
0
0
0
24
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
24
0
0
0
8
0
0
0
0
0
0
0
31
0
% N
% Pro:
0
62
16
0
24
24
24
0
24
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
8
0
0
0
0
24
77
0
16
0
% Q
% Arg:
0
0
0
0
0
16
0
0
0
0
0
0
0
0
8
% R
% Ser:
16
0
16
31
0
0
0
31
8
24
0
0
0
8
8
% S
% Thr:
0
0
0
0
8
0
0
0
8
62
0
0
0
0
0
% T
% Val:
8
8
0
16
54
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
47
0
0
0
0
8
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _