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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDPK1
All Species:
23.94
Human Site:
Y299
Identified Species:
43.89
UniProt:
O15530
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15530
NP_002604.1
556
63152
Y299
Q
K
I
I
K
L
E
Y
D
F
P
E
K
F
F
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537000
560
63701
Y303
Q
K
I
I
K
L
E
Y
D
F
P
E
K
F
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2A0
559
63740
Y302
Q
K
I
I
K
L
E
Y
H
F
P
E
K
F
F
Rat
Rattus norvegicus
O55173
559
63591
Y302
Q
K
I
I
K
L
E
Y
D
F
P
E
K
F
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518589
320
36424
H108
L
H
G
K
G
I
I
H
R
D
L
K
P
E
N
Chicken
Gallus gallus
Q6U1I9
432
48872
V220
Y
L
H
S
L
N
I
V
Y
R
D
L
K
P
E
Frog
Xenopus laevis
Q6GPN6
434
49096
V222
Y
L
H
S
L
N
I
V
Y
R
D
L
K
P
E
Zebra Danio
Brachydanio rerio
Q7ZTW4
433
48964
V221
Y
L
H
S
L
N
I
V
Y
R
D
L
K
P
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W0V1
836
94060
V527
K
E
I
L
D
C
A
V
D
F
P
Q
G
F
D
Honey Bee
Apis mellifera
XP_394208
537
61368
Y293
Q
K
I
L
K
L
E
Y
E
I
P
D
G
F
C
Nematode Worm
Caenorhab. elegans
Q9Y1J3
636
71898
F327
K
R
I
Q
E
L
D
F
S
F
P
E
G
F
P
Sea Urchin
Strong. purpuratus
XP_786576
539
61612
Y304
Q
K
I
I
K
L
E
Y
D
F
P
D
G
F
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12236
1081
121642
Y406
Q
K
V
M
K
V
Q
Y
A
F
T
P
G
F
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
93.3
N.A.
94.8
95.3
N.A.
52.1
28.6
28
27.5
N.A.
32.5
54.1
32.5
58
Protein Similarity:
100
N.A.
N.A.
95
N.A.
96.2
96.4
N.A.
54.6
44
43.8
43.3
N.A.
44.1
66.1
52.2
70.3
P-Site Identity:
100
N.A.
N.A.
100
N.A.
93.3
100
N.A.
0
6.6
6.6
6.6
N.A.
33.3
60
40
80
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
93.3
100
N.A.
20
6.6
6.6
6.6
N.A.
60
80
73.3
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
35.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
8
0
8
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
8
% C
% Asp:
0
0
0
0
8
0
8
0
39
8
24
16
0
0
8
% D
% Glu:
0
8
0
0
8
0
47
0
8
0
0
39
0
8
24
% E
% Phe:
0
0
0
0
0
0
0
8
0
62
0
0
0
70
31
% F
% Gly:
0
0
8
0
8
0
0
0
0
0
0
0
39
0
0
% G
% His:
0
8
24
0
0
0
0
8
8
0
0
0
0
0
0
% H
% Ile:
0
0
62
39
0
8
31
0
0
8
0
0
0
0
0
% I
% Lys:
16
54
0
8
54
0
0
0
0
0
0
8
54
0
0
% K
% Leu:
8
24
0
16
24
54
0
0
0
0
8
24
0
0
0
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
24
0
0
0
0
0
0
0
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
62
8
8
24
16
% P
% Gln:
54
0
0
8
0
0
8
0
0
0
0
8
0
0
0
% Q
% Arg:
0
8
0
0
0
0
0
0
8
24
0
0
0
0
0
% R
% Ser:
0
0
0
24
0
0
0
0
8
0
0
0
0
0
8
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% T
% Val:
0
0
8
0
0
8
0
31
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
24
0
0
0
0
0
0
54
24
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _