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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RS1 All Species: 16.06
Human Site: S51 Identified Species: 35.33
UniProt: O15537 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15537 NP_000321.1 224 25592 S51 G G P N A L W S A G A T S L D
Chimpanzee Pan troglodytes XP_001163679 80 9575
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_548882 224 25626 S51 G S P N G L W S A G A T S L D
Cat Felis silvestris
Mouse Mus musculus Q9Z1L4 224 25556 S51 V G A N A L W S A G A T S L D
Rat Rattus norvegicus NP_001098113 224 25516 S51 G G A N A L W S A G A A S L D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521862 164 18408
Chicken Gallus gallus NP_001128447 225 25576 S52 G P N S V W S S G T N S L E C
Frog Xenopus laevis NP_001090420 237 27032 I64 G G Y G S S L I N R M I A S D
Zebra Danio Brachydanio rerio NP_001003438 230 26187 S57 K M L S K G S S S W P Q E M G
Tiger Blowfish Takifugu rubipres Q9W6R5 280 32014 S107 F P S I R T G S S M V R G V D
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_793834 378 41730 S165 L T W T N H I S M R F D I L G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 32.1 N.A. 95.5 N.A. 95.9 96.4 N.A. 54.9 78.6 65.8 65.6 53.5 N.A. N.A. N.A. 23
Protein Similarity: 100 34.3 N.A. 96.8 N.A. 97.3 97.3 N.A. 60.2 88 77.2 81.7 69.6 N.A. N.A. N.A. 35.9
P-Site Identity: 100 0 N.A. 86.6 N.A. 86.6 86.6 N.A. 0 13.3 20 6.6 13.3 N.A. N.A. N.A. 13.3
P-Site Similarity: 100 0 N.A. 86.6 N.A. 86.6 86.6 N.A. 0 26.6 33.3 26.6 26.6 N.A. N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 19 0 28 0 0 0 37 0 37 10 10 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 55 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 10 10 0 % E
% Phe: 10 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % F
% Gly: 46 37 0 10 10 10 10 0 10 37 0 0 10 0 19 % G
% His: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 10 0 0 10 10 0 0 0 10 10 0 0 % I
% Lys: 10 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 10 0 10 0 0 37 10 0 0 0 0 0 10 46 0 % L
% Met: 0 10 0 0 0 0 0 0 10 10 10 0 0 10 0 % M
% Asn: 0 0 10 37 10 0 0 0 10 0 10 0 0 0 0 % N
% Pro: 0 19 19 0 0 0 0 0 0 0 10 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % Q
% Arg: 0 0 0 0 10 0 0 0 0 19 0 10 0 0 0 % R
% Ser: 0 10 10 19 10 10 19 73 19 0 0 10 37 10 0 % S
% Thr: 0 10 0 10 0 10 0 0 0 10 0 28 0 0 0 % T
% Val: 10 0 0 0 10 0 0 0 0 0 10 0 0 10 0 % V
% Trp: 0 0 10 0 0 10 37 0 0 10 0 0 0 0 0 % W
% Tyr: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _