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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RGS5
All Species:
24.24
Human Site:
S54
Identified Species:
59.26
UniProt:
O15539
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15539
NP_003608.1
181
20946
S54
P
A
K
T
Q
K
T
S
L
D
E
A
L
Q
W
Chimpanzee
Pan troglodytes
XP_001174440
181
20940
S54
P
A
K
T
Q
K
P
S
L
D
E
S
L
Q
W
Rhesus Macaque
Macaca mulatta
XP_001082591
181
20933
S54
P
A
K
T
H
K
P
S
L
D
E
A
L
Q
W
Dog
Lupus familis
XP_545784
181
20935
S54
P
A
K
T
Q
K
P
S
L
D
E
A
L
Q
W
Cat
Felis silvestris
Mouse
Mus musculus
O08850
181
21067
S54
P
A
K
A
H
K
P
S
L
E
E
V
L
Q
W
Rat
Rattus norvegicus
P49800
181
21034
S54
P
A
K
A
H
K
P
S
L
E
E
V
L
Q
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516935
166
18976
E41
K
A
P
K
V
S
L
E
E
V
T
C
P
R
S
Chicken
Gallus gallus
Q7SZC6
208
23504
S52
V
S
S
S
Q
R
V
S
Q
E
E
V
K
K
W
Frog
Xenopus laevis
A1A643
201
23280
T65
D
T
E
K
N
K
L
T
P
N
E
I
I
Q
W
Zebra Danio
Brachydanio rerio
Q6DGI0
174
20503
I49
R
W
A
D
S
F
D
I
L
L
S
N
K
Y
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
98.3
95
N.A.
90
89.5
N.A.
64.6
46.6
37.3
48.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.4
98.9
97.7
N.A.
93.9
93.3
N.A.
72.9
66.3
57.2
64.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
86.6
86.6
93.3
N.A.
66.6
66.6
N.A.
6.6
26.6
26.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
86.6
93.3
N.A.
73.3
73.3
N.A.
13.3
60
53.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
70
10
20
0
0
0
0
0
0
0
30
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% C
% Asp:
10
0
0
10
0
0
10
0
0
40
0
0
0
0
0
% D
% Glu:
0
0
10
0
0
0
0
10
10
30
80
0
0
0
0
% E
% Phe:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% G
% His:
0
0
0
0
30
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
10
0
0
0
10
10
0
0
% I
% Lys:
10
0
60
20
0
70
0
0
0
0
0
0
20
10
0
% K
% Leu:
0
0
0
0
0
0
20
0
70
10
0
0
60
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
0
0
10
0
10
0
0
0
% N
% Pro:
60
0
10
0
0
0
50
0
10
0
0
0
10
0
0
% P
% Gln:
0
0
0
0
40
0
0
0
10
0
0
0
0
70
0
% Q
% Arg:
10
0
0
0
0
10
0
0
0
0
0
0
0
10
0
% R
% Ser:
0
10
10
10
10
10
0
70
0
0
10
10
0
0
10
% S
% Thr:
0
10
0
40
0
0
10
10
0
0
10
0
0
0
0
% T
% Val:
10
0
0
0
10
0
10
0
0
10
0
30
0
0
0
% V
% Trp:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
80
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _