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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RNF113A All Species: 25.45
Human Site: S95 Identified Species: 35
UniProt: O15541 Number Species: 16
    Phosphosite Substitution
    Charge Score: -0.06
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15541 NP_008909.1 343 38787 S95 E E E N E P E S L G V V Y K S
Chimpanzee Pan troglodytes XP_529135 343 38768 S95 E E E N E P E S L G V V Y K S
Rhesus Macaque Macaca mulatta XP_001083433 344 38832 S95 E E E N E P E S L G V V Y K S
Dog Lupus familis XP_538154 348 39406 S100 E E E N E S E S L G V V Y K S
Cat Felis silvestris
Mouse Mus musculus NP_079801 337 38041 S95 E E K A G N E S L G V V Y K S
Rat Rattus norvegicus NP_001004445 337 38010 S95 E E K A G N E S L G V V Y K S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509909 347 38316 G99 G D E E E P P G L G V A Y R S
Chicken Gallus gallus NP_001004396 328 37759 E83 D D D D P S K E I G V T Y K S
Frog Xenopus laevis NP_001087087 319 36679 S80 E E E K S G K S I T V S Y K S
Zebra Danio Brachydanio rerio NP_001004536 321 36768 K82 S E E E K E E K S V T V A Y K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650865 357 39775 K93 S S A S D D D K L G I A Y K S
Honey Bee Apis mellifera XP_001121039 282 32433 V43 S E E E S I T V S Y K S S R T
Nematode Worm Caenorhab. elegans O17917 384 43409 S89 A S G D A G P S G P R D Q G A
Sea Urchin Strong. purpuratus XP_780983 697 77998 D446 S S E E E S K D T M V S Y K S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8GX84 343 38691 P93 S T T T S G A P E R S V F H Y
Baker's Yeast Sacchar. cerevisiae P53769 259 29722 R20 D E K N Q K K R Q K I N F S E
Red Bread Mold Neurospora crassa Q7SDY3 405 44422 Y114 Q I R S N T I Y E A D R D A A
Conservation
Percent
Protein Identity: 100 99.7 97.6 93.6 N.A. 89.5 88.9 N.A. 72.3 74.3 68.8 69.3 N.A. 52.6 53.6 38.7 30.4
Protein Similarity: 100 100 98.2 94.2 N.A. 92.7 92.4 N.A. 82.4 83.6 80.1 79.3 N.A. 66.3 63.8 54.6 38.8
P-Site Identity: 100 100 100 93.3 N.A. 73.3 73.3 N.A. 53.3 33.3 53.3 26.6 N.A. 33.3 13.3 6.6 40
P-Site Similarity: 100 100 100 93.3 N.A. 80 80 N.A. 66.6 73.3 66.6 33.3 N.A. 60 26.6 20 46.6
Percent
Protein Identity: N.A. N.A. N.A. 37.6 27.9 30.6
Protein Similarity: N.A. N.A. N.A. 54.8 47.2 44.2
P-Site Identity: N.A. N.A. N.A. 6.6 13.3 0
P-Site Similarity: N.A. N.A. N.A. 13.3 53.3 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 6 0 6 12 6 0 6 0 0 6 0 12 6 6 12 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 12 12 6 12 6 6 6 6 0 0 6 6 6 0 0 % D
% Glu: 42 59 53 24 36 6 42 6 12 0 0 0 0 0 6 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 12 0 0 % F
% Gly: 6 0 6 0 12 18 0 6 6 53 0 0 0 6 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 6 0 % H
% Ile: 0 6 0 0 0 6 6 0 12 0 12 0 0 0 0 % I
% Lys: 0 0 18 6 6 6 24 12 0 6 6 0 0 59 6 % K
% Leu: 0 0 0 0 0 0 0 0 48 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 6 0 0 0 0 0 % M
% Asn: 0 0 0 30 6 12 0 0 0 0 0 6 0 0 0 % N
% Pro: 0 0 0 0 6 24 12 6 0 6 0 0 0 0 0 % P
% Gln: 6 0 0 0 6 0 0 0 6 0 0 0 6 0 0 % Q
% Arg: 0 0 6 0 0 0 0 6 0 6 6 6 0 12 0 % R
% Ser: 30 18 0 12 18 18 0 48 12 0 6 18 6 6 65 % S
% Thr: 0 6 6 6 0 6 6 0 6 6 6 6 0 0 6 % T
% Val: 0 0 0 0 0 0 0 6 0 6 59 48 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 6 0 6 0 0 65 6 6 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _