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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RNF113A All Species: 23.33
Human Site: T52 Identified Species: 32.08
UniProt: O15541 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0.06
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15541 NP_008909.1 343 38787 T52 S S S D E G C T V V R P E K K
Chimpanzee Pan troglodytes XP_529135 343 38768 T52 S S S D E G C T V V R P E K K
Rhesus Macaque Macaca mulatta XP_001083433 344 38832 T52 S S S D E G C T V V R P E K K
Dog Lupus familis XP_538154 348 39406 P57 E G S T V V R P E K K R A I H
Cat Felis silvestris
Mouse Mus musculus NP_079801 337 38041 S52 S S S D E G C S V V R P E K K
Rat Rattus norvegicus NP_001004445 337 38010 T52 S S S D E G C T V V R P E K K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509909 347 38316 G56 S S S S S D E G S A V V R R E
Chicken Gallus gallus NP_001004396 328 37759 G40 Q E S S G E E G S T V V R K E
Frog Xenopus laevis NP_001087087 319 36679 K37 N E S S E E E K G P V I R R I
Zebra Danio Brachydanio rerio NP_001004536 321 36768 S39 D S D K E K S S G D E G S A V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650865 357 39775 L50 T K G K A S A L V R A E N R R
Honey Bee Apis mellifera XP_001121039 282 32433
Nematode Worm Caenorhab. elegans O17917 384 43409 S46 R T N P M V Q S T K Q L D A S
Sea Urchin Strong. purpuratus XP_780983 697 77998 E403 D T D K S S G E E E S A V V R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8GX84 343 38691 D50 R K R T I D A D E E D G D S K
Baker's Yeast Sacchar. cerevisiae P53769 259 29722
Red Bread Mold Neurospora crassa Q7SDY3 405 44422 T71 E S S E D E A T G Q R I K R R
Conservation
Percent
Protein Identity: 100 99.7 97.6 93.6 N.A. 89.5 88.9 N.A. 72.3 74.3 68.8 69.3 N.A. 52.6 53.6 38.7 30.4
Protein Similarity: 100 100 98.2 94.2 N.A. 92.7 92.4 N.A. 82.4 83.6 80.1 79.3 N.A. 66.3 63.8 54.6 38.8
P-Site Identity: 100 100 100 6.6 N.A. 93.3 100 N.A. 20 13.3 13.3 13.3 N.A. 6.6 0 0 0
P-Site Similarity: 100 100 100 13.3 N.A. 100 100 N.A. 33.3 20 26.6 20 N.A. 26.6 0 33.3 13.3
Percent
Protein Identity: N.A. N.A. N.A. 37.6 27.9 30.6
Protein Similarity: N.A. N.A. N.A. 54.8 47.2 44.2
P-Site Identity: N.A. N.A. N.A. 6.6 0 26.6
P-Site Similarity: N.A. N.A. N.A. 13.3 0 60
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 6 0 18 0 0 6 6 6 6 12 0 % A
% Cys: 0 0 0 0 0 0 30 0 0 0 0 0 0 0 0 % C
% Asp: 12 0 12 30 6 12 0 6 0 6 6 0 12 0 0 % D
% Glu: 12 12 0 6 42 18 18 6 18 12 6 6 30 0 12 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 6 6 0 6 30 6 12 18 0 0 12 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6 % H
% Ile: 0 0 0 0 6 0 0 0 0 0 0 12 0 6 6 % I
% Lys: 0 12 0 18 0 6 0 6 0 12 6 0 6 36 36 % K
% Leu: 0 0 0 0 0 0 0 6 0 0 0 6 0 0 0 % L
% Met: 0 0 0 0 6 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 6 0 6 0 0 0 0 0 0 0 0 0 6 0 0 % N
% Pro: 0 0 0 6 0 0 0 6 0 6 0 30 0 0 0 % P
% Gln: 6 0 0 0 0 0 6 0 0 6 6 0 0 0 0 % Q
% Arg: 12 0 6 0 0 0 6 0 0 6 36 6 18 24 18 % R
% Ser: 36 48 59 18 12 12 6 18 12 0 6 0 6 6 6 % S
% Thr: 6 12 0 12 0 0 0 30 6 6 0 0 0 0 0 % T
% Val: 0 0 0 0 6 12 0 0 36 30 18 12 6 6 6 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _