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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RNF113A All Species: 39.39
Human Site: Y100 Identified Species: 54.17
UniProt: O15541 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0.06
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15541 NP_008909.1 343 38787 Y100 P E S L G V V Y K S T R S A K
Chimpanzee Pan troglodytes XP_529135 343 38768 Y100 P E S L G V V Y K S T R S A K
Rhesus Macaque Macaca mulatta XP_001083433 344 38832 Y100 P E S L G V V Y K S T R S A K
Dog Lupus familis XP_538154 348 39406 Y105 S E S L G V V Y K S T R S A K
Cat Felis silvestris
Mouse Mus musculus NP_079801 337 38041 Y100 N E S L G V V Y K S T R S A K
Rat Rattus norvegicus NP_001004445 337 38010 Y100 N E S L G V V Y K S T R S A K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509909 347 38316 Y104 P P G L G V A Y R S T R S A K
Chicken Gallus gallus NP_001004396 328 37759 Y88 S K E I G V T Y K S T R S A K
Frog Xenopus laevis NP_001087087 319 36679 Y85 G K S I T V S Y K S T R S A K
Zebra Danio Brachydanio rerio NP_001004536 321 36768 A87 E E K S V T V A Y K S T R S A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650865 357 39775 Y98 D D K L G I A Y K S K R E A L
Honey Bee Apis mellifera XP_001121039 282 32433 S48 I T V S Y K S S R T P M P A G
Nematode Worm Caenorhab. elegans O17917 384 43409 Q94 G P S G P R D Q G A T A T L E
Sea Urchin Strong. purpuratus XP_780983 697 77998 Y451 S K D T M V S Y K S S R S A K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8GX84 343 38691 F98 G A P E R S V F H Y D S S K E
Baker's Yeast Sacchar. cerevisiae P53769 259 29722 F25 K K R Q K I N F S E E K L V A
Red Bread Mold Neurospora crassa Q7SDY3 405 44422 D119 T I Y E A D R D A A L R L D A
Conservation
Percent
Protein Identity: 100 99.7 97.6 93.6 N.A. 89.5 88.9 N.A. 72.3 74.3 68.8 69.3 N.A. 52.6 53.6 38.7 30.4
Protein Similarity: 100 100 98.2 94.2 N.A. 92.7 92.4 N.A. 82.4 83.6 80.1 79.3 N.A. 66.3 63.8 54.6 38.8
P-Site Identity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. 73.3 66.6 66.6 13.3 N.A. 46.6 6.6 13.3 53.3
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. 80 80 80 26.6 N.A. 60 20 33.3 66.6
Percent
Protein Identity: N.A. N.A. N.A. 37.6 27.9 30.6
Protein Similarity: N.A. N.A. N.A. 54.8 47.2 44.2
P-Site Identity: N.A. N.A. N.A. 13.3 0 6.6
P-Site Similarity: N.A. N.A. N.A. 26.6 26.6 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 6 0 0 6 0 12 6 6 12 0 6 0 71 18 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 6 6 6 0 0 6 6 6 0 0 6 0 0 6 0 % D
% Glu: 6 42 6 12 0 0 0 0 0 6 6 0 6 0 12 % E
% Phe: 0 0 0 0 0 0 0 12 0 0 0 0 0 0 0 % F
% Gly: 18 0 6 6 53 0 0 0 6 0 0 0 0 0 6 % G
% His: 0 0 0 0 0 0 0 0 6 0 0 0 0 0 0 % H
% Ile: 6 6 0 12 0 12 0 0 0 0 0 0 0 0 0 % I
% Lys: 6 24 12 0 6 6 0 0 59 6 6 6 0 6 59 % K
% Leu: 0 0 0 48 0 0 0 0 0 0 6 0 12 6 6 % L
% Met: 0 0 0 0 6 0 0 0 0 0 0 6 0 0 0 % M
% Asn: 12 0 0 0 0 0 6 0 0 0 0 0 0 0 0 % N
% Pro: 24 12 6 0 6 0 0 0 0 0 6 0 6 0 0 % P
% Gln: 0 0 0 6 0 0 0 6 0 0 0 0 0 0 0 % Q
% Arg: 0 0 6 0 6 6 6 0 12 0 0 71 6 0 0 % R
% Ser: 18 0 48 12 0 6 18 6 6 65 12 6 65 6 0 % S
% Thr: 6 6 0 6 6 6 6 0 0 6 59 6 6 0 0 % T
% Val: 0 0 6 0 6 59 48 0 0 0 0 0 0 6 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 6 0 6 0 0 65 6 6 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _