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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RNF113A
All Species:
31.82
Human Site:
Y297
Identified Species:
43.75
UniProt:
O15541
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15541
NP_008909.1
343
38787
Y297
F
R
T
T
P
R
C
Y
V
C
D
Q
Q
T
N
Chimpanzee
Pan troglodytes
XP_529135
343
38768
Y297
F
R
T
T
P
R
C
Y
V
C
D
Q
Q
T
N
Rhesus Macaque
Macaca mulatta
XP_001083433
344
38832
Y297
F
R
T
T
P
R
C
Y
V
C
D
Q
Q
T
N
Dog
Lupus familis
XP_538154
348
39406
Y302
F
R
T
T
P
R
C
Y
V
C
D
Q
Q
T
N
Cat
Felis silvestris
Mouse
Mus musculus
NP_079801
337
38041
Y297
F
R
T
T
P
R
C
Y
V
C
E
Q
Q
T
H
Rat
Rattus norvegicus
NP_001004445
337
38010
Y297
F
R
T
T
P
R
C
Y
V
C
E
Q
Q
T
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509909
347
38316
Y301
Y
R
I
S
Q
R
C
Y
V
C
D
R
Q
T
N
Chicken
Gallus gallus
NP_001004396
328
37759
Y285
Y
R
K
S
Q
R
C
Y
V
C
D
K
Q
T
N
Frog
Xenopus laevis
NP_001087087
319
36679
Q279
L
E
H
Y
R
K
S
Q
R
C
Y
V
C
N
T
Zebra Danio
Brachydanio rerio
NP_001004536
321
36768
S281
A
L
Q
H
Y
R
K
S
K
R
C
Y
V
C
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650865
357
39775
I299
Y
K
K
S
Q
R
C
I
I
C
S
Q
Q
T
N
Honey Bee
Apis mellifera
XP_001121039
282
32433
T242
L
D
Q
Y
K
K
S
T
R
C
Y
I
C
N
V
Nematode Worm
Caenorhab. elegans
O17917
384
43409
A307
K
Q
Q
Q
K
Q
E
A
E
K
Q
E
E
E
K
Sea Urchin
Strong. purpuratus
XP_780983
697
77998
R648
K
H
Y
K
K
S
K
R
C
F
V
C
G
T
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8GX84
343
38691
A301
H
Y
F
C
E
H
C
A
L
K
H
H
T
K
N
Baker's Yeast
Sacchar. cerevisiae
P53769
259
29722
C219
T
N
C
G
H
Y
F
C
G
S
C
F
A
K
D
Red Bread Mold
Neurospora crassa
Q7SDY3
405
44422
V322
G
P
Y
S
N
S
P
V
V
T
R
C
G
H
Y
Conservation
Percent
Protein Identity:
100
99.7
97.6
93.6
N.A.
89.5
88.9
N.A.
72.3
74.3
68.8
69.3
N.A.
52.6
53.6
38.7
30.4
Protein Similarity:
100
100
98.2
94.2
N.A.
92.7
92.4
N.A.
82.4
83.6
80.1
79.3
N.A.
66.3
63.8
54.6
38.8
P-Site Identity:
100
100
100
100
N.A.
86.6
86.6
N.A.
66.6
66.6
6.6
13.3
N.A.
46.6
6.6
0
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
86.6
86.6
13.3
13.3
N.A.
73.3
13.3
26.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.6
27.9
30.6
Protein Similarity:
N.A.
N.A.
N.A.
54.8
47.2
44.2
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
20
6.6
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
0
0
0
0
0
0
12
0
0
0
0
6
0
0
% A
% Cys:
0
0
6
6
0
0
59
6
6
65
12
12
12
6
0
% C
% Asp:
0
6
0
0
0
0
0
0
0
0
36
0
0
0
6
% D
% Glu:
0
6
0
0
6
0
6
0
6
0
12
6
6
6
0
% E
% Phe:
36
0
6
0
0
0
6
0
0
6
0
6
0
0
0
% F
% Gly:
6
0
0
6
0
0
0
0
6
0
0
0
12
0
0
% G
% His:
6
6
6
6
6
6
0
0
0
0
6
6
0
6
12
% H
% Ile:
0
0
6
0
0
0
0
6
6
0
0
6
0
0
0
% I
% Lys:
12
6
12
6
18
12
12
0
6
12
0
6
0
12
6
% K
% Leu:
12
6
0
0
0
0
0
0
6
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
6
0
0
6
0
0
0
0
0
0
0
0
12
53
% N
% Pro:
0
6
0
0
36
0
6
0
0
0
0
0
0
0
0
% P
% Gln:
0
6
18
6
18
6
0
6
0
0
6
42
53
0
6
% Q
% Arg:
0
48
0
0
6
59
0
6
12
6
6
6
0
0
0
% R
% Ser:
0
0
0
24
0
12
12
6
0
6
6
0
0
0
0
% S
% Thr:
6
0
36
36
0
0
0
6
0
6
0
0
6
59
6
% T
% Val:
0
0
0
0
0
0
0
6
53
0
6
6
6
0
6
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
18
6
12
12
6
6
0
48
0
0
12
6
0
0
6
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _