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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
P2RX6
All Species:
11.21
Human Site:
T412
Identified Species:
27.41
UniProt:
O15547
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15547
NP_001153026.1
431
47913
T412
A
A
G
S
Q
T
Q
T
P
G
W
P
C
P
S
Chimpanzee
Pan troglodytes
XP_001168351
441
48812
T422
A
A
G
S
Q
T
Q
T
P
G
W
P
C
P
S
Rhesus Macaque
Macaca mulatta
XP_001084368
438
48443
T420
A
T
A
A
G
S
Q
T
Q
T
P
G
W
P
C
Dog
Lupus familis
XP_543562
527
57557
T509
G
T
Q
S
G
N
Q
T
P
T
A
E
W
P
C
Cat
Felis silvestris
Mouse
Mus musculus
O54803
379
42097
Y361
V
D
R
E
A
G
F
Y
W
R
T
K
Y
E
E
Rat
Rattus norvegicus
P51579
379
42432
Y361
V
D
R
E
A
G
F
Y
W
R
T
K
Y
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514747
385
42456
Y367
A
F
Y
S
G
V
K
Y
E
E
A
K
A
P
K
Chicken
Gallus gallus
NP_990079
402
45138
S384
V
K
S
S
S
R
K
S
L
T
S
P
T
L
N
Frog
Xenopus laevis
NP_001082067
391
44317
Y373
H
Y
Y
R
E
K
K
Y
K
Y
V
E
D
Y
D
Zebra Danio
Brachydanio rerio
NP_919394
481
54639
Q419
E
K
P
T
A
E
M
Q
P
L
T
S
I
L
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.8
92.4
63.1
N.A.
72.8
70.3
N.A.
59.1
48.2
39.9
42.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
97
94.9
68.6
N.A.
77.7
77.2
N.A.
68.9
64
58.4
56.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
26.6
33.3
N.A.
0
0
N.A.
20
13.3
0
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
40
33.3
N.A.
0
0
N.A.
26.6
33.3
13.3
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
40
20
10
10
30
0
0
0
0
0
20
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
20
0
20
% C
% Asp:
0
20
0
0
0
0
0
0
0
0
0
0
10
0
10
% D
% Glu:
10
0
0
20
10
10
0
0
10
10
0
20
0
20
20
% E
% Phe:
0
10
0
0
0
0
20
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
20
0
30
20
0
0
0
20
0
10
0
0
0
% G
% His:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% I
% Lys:
0
20
0
0
0
10
30
0
10
0
0
30
0
0
10
% K
% Leu:
0
0
0
0
0
0
0
0
10
10
0
0
0
20
0
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
10
% N
% Pro:
0
0
10
0
0
0
0
0
40
0
10
30
0
50
0
% P
% Gln:
0
0
10
0
20
0
40
10
10
0
0
0
0
0
0
% Q
% Arg:
0
0
20
10
0
10
0
0
0
20
0
0
0
0
0
% R
% Ser:
0
0
10
50
10
10
0
10
0
0
10
10
0
0
20
% S
% Thr:
0
20
0
10
0
20
0
40
0
30
30
0
10
0
10
% T
% Val:
30
0
0
0
0
10
0
0
0
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
20
0
20
0
20
0
0
% W
% Tyr:
0
10
20
0
0
0
0
40
0
10
0
0
20
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _