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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MEFV
All Species:
3.94
Human Site:
S703
Identified Species:
12.38
UniProt:
O15553
Number Species:
7
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15553
NP_000234.1
781
86444
S703
E
N
E
Y
Q
A
S
S
V
P
P
T
R
L
L
Chimpanzee
Pan troglodytes
Q1XHU0
518
59727
P445
K
Y
A
A
T
T
T
P
F
T
P
L
H
I
K
Rhesus Macaque
Macaca mulatta
Q5TM55
465
52195
S392
G
V
W
A
V
I
I
S
H
Q
Q
C
W
A
S
Dog
Lupus familis
XP_547161
793
89168
T715
R
S
E
Y
Q
V
S
T
I
P
P
T
R
L
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJ26
767
86246
D687
G
A
H
T
Q
D
C
D
V
V
F
Y
P
E
R
Rat
Rattus norvegicus
Q9JJ25
750
83976
A670
P
S
T
T
K
A
Q
A
L
I
P
T
V
H
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509541
527
60558
A454
L
W
N
R
D
V
Y
A
A
L
T
S
N
P
T
Chicken
Gallus gallus
Frog
Xenopus laevis
Q91431
610
69096
L537
N
G
N
R
Y
K
A
L
E
S
P
S
K
A
L
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
27.3
23.1
60.7
N.A.
31.1
23.8
N.A.
28.5
N.A.
24.5
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
40.5
35.5
72.6
N.A.
47.1
40
N.A.
42
N.A.
40.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
6.6
60
N.A.
13.3
26.6
N.A.
0
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
6.6
80
N.A.
13.3
53.3
N.A.
13.3
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
13
13
25
0
25
13
25
13
0
0
0
0
25
0
% A
% Cys:
0
0
0
0
0
0
13
0
0
0
0
13
0
0
0
% C
% Asp:
0
0
0
0
13
13
0
13
0
0
0
0
0
0
0
% D
% Glu:
13
0
25
0
0
0
0
0
13
0
0
0
0
13
0
% E
% Phe:
0
0
0
0
0
0
0
0
13
0
13
0
0
0
0
% F
% Gly:
25
13
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
13
0
0
0
0
0
13
0
0
0
13
13
0
% H
% Ile:
0
0
0
0
0
13
13
0
13
13
0
0
0
13
0
% I
% Lys:
13
0
0
0
13
13
0
0
0
0
0
0
13
0
13
% K
% Leu:
13
0
0
0
0
0
0
13
13
13
0
13
0
25
38
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
13
13
25
0
0
0
0
0
0
0
0
0
13
0
0
% N
% Pro:
13
0
0
0
0
0
0
13
0
25
63
0
13
13
0
% P
% Gln:
0
0
0
0
38
0
13
0
0
13
13
0
0
0
13
% Q
% Arg:
13
0
0
25
0
0
0
0
0
0
0
0
25
0
13
% R
% Ser:
0
25
0
0
0
0
25
25
0
13
0
25
0
0
13
% S
% Thr:
0
0
13
25
13
13
13
13
0
13
13
38
0
0
13
% T
% Val:
0
13
0
0
13
25
0
0
25
13
0
0
13
0
0
% V
% Trp:
0
13
13
0
0
0
0
0
0
0
0
0
13
0
0
% W
% Tyr:
0
13
0
25
13
0
13
0
0
0
0
13
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _