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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KCNN4 All Species: 10.3
Human Site: Y379 Identified Species: 22.67
UniProt: O15554 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15554 NP_002241.1 427 47696 Y379 S K M H M I L Y D L Q Q N L S
Chimpanzee Pan troglodytes XP_512722 385 43303 Y337 S K M H M I L Y D L Q Q N L S
Rhesus Macaque Macaca mulatta XP_001101360 251 28074 D204 K M H M I L Y D L Q Q N L S S
Dog Lupus familis XP_541579 427 47648 C379 S K M H M I L C D L Q L G L S
Cat Felis silvestris
Mouse Mus musculus O89109 425 47765 C377 S K M H M I L C D L Q L G L S
Rat Rattus norvegicus Q9QYW1 425 47748 C377 S K M H M I L C D L Q L G L S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521824 487 53009 C351 S K V K L L F C E L A V G R E
Chicken Gallus gallus NP_990129 553 61999 Y464 A K T Q N I M Y D M I S D L N
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_696782 747 85306 C686 S K M Q M I M C D L S A N W N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7KVW5 924 101426 Y838 A K T Q N T V Y E I I S D M S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q11122 471 54319 R424 R S V K S E M R E F S E N N S
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 88.5 57.6 90.6 N.A. 87.1 85.9 N.A. 51.7 37.2 N.A. 28.9 N.A. 21.6 N.A. 27.8 N.A.
Protein Similarity: 100 89.2 58 93.9 N.A. 91.5 90.8 N.A. 58.9 50.8 N.A. 38.1 N.A. 31.9 N.A. 47.5 N.A.
P-Site Identity: 100 100 13.3 80 N.A. 80 80 N.A. 20 33.3 N.A. 53.3 N.A. 20 N.A. 13.3 N.A.
P-Site Similarity: 100 100 26.6 80 N.A. 80 80 N.A. 46.6 66.6 N.A. 66.6 N.A. 60 N.A. 40 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 19 0 0 0 0 0 0 0 0 0 10 10 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 46 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 10 64 0 0 0 19 0 0 % D
% Glu: 0 0 0 0 0 10 0 0 28 0 0 10 0 0 10 % E
% Phe: 0 0 0 0 0 0 10 0 0 10 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 37 0 0 % G
% His: 0 0 10 46 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 10 64 0 0 0 10 19 0 0 0 0 % I
% Lys: 10 82 0 19 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 10 19 46 0 10 64 0 28 10 55 0 % L
% Met: 0 10 55 10 55 0 28 0 0 10 0 0 0 10 0 % M
% Asn: 0 0 0 0 19 0 0 0 0 0 0 10 37 10 19 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 28 0 0 0 0 0 10 55 19 0 0 0 % Q
% Arg: 10 0 0 0 0 0 0 10 0 0 0 0 0 10 0 % R
% Ser: 64 10 0 0 10 0 0 0 0 0 19 19 0 10 73 % S
% Thr: 0 0 19 0 0 10 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 19 0 0 0 10 0 0 0 0 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % W
% Tyr: 0 0 0 0 0 0 10 37 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _