Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DHX15 All Species: 24.24
Human Site: S227 Identified Species: 35.56
UniProt: O43143 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43143 NP_001349.2 795 90933 S227 S I R F E D C S S A K T I L K
Chimpanzee Pan troglodytes Q7YR39 1044 119631 T490 S I R F E D C T S E R T V L R
Rhesus Macaque Macaca mulatta XP_001106067 795 90884 S227 S I R F E D C S S A K T I L K
Dog Lupus familis XP_851535 795 91016 S227 S I R F E D C S S A K T I L K
Cat Felis silvestris
Mouse Mus musculus O35286 795 90988 S227 S I R F E D C S S A K T I L K
Rat Rattus norvegicus Q5XI69 779 88496 G232 C P I F D I P G R L Y P V R E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513650 820 93995 S252 S I R F E D C S S A K T I L K
Chicken Gallus gallus NP_001026330 762 87695 I225 L E R Y G V I I L D E A H E R
Frog Xenopus laevis Q5XH12 748 85094 S222 V V I I T C P S L S G T L V S
Zebra Danio Brachydanio rerio NP_001108613 769 88372 M220 G M L L R E A M N D P L L E R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610269 729 82633 E211 I L M G V L K E V I R Q R S D
Honey Bee Apis mellifera XP_392081 718 81782 V211 Q R P D L K L V I M S A T L D
Nematode Worm Caenorhab. elegans Q20875 739 84370 L211 D E A H E R T L A T D I L M G
Sea Urchin Strong. purpuratus O17438 455 51461
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O22899 729 82635 R212 G L L K E V L R N R P D L K L
Baker's Yeast Sacchar. cerevisiae P53131 767 87543 E216 Y S C I I L D E A H E R T L A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 37.1 99.8 99.7 N.A. 99.6 39.2 N.A. 85.9 92.4 37.8 89 N.A. 71.6 74.3 68.5 50.6
Protein Similarity: 100 51.1 99.8 99.7 N.A. 99.7 57.1 N.A. 87.3 94.8 57.3 93.5 N.A. 81.8 82.6 78.8 54
P-Site Identity: 100 66.6 100 100 N.A. 100 6.6 N.A. 100 6.6 13.3 0 N.A. 0 6.6 6.6 0
P-Site Similarity: 100 93.3 100 100 N.A. 100 26.6 N.A. 100 26.6 40 33.3 N.A. 13.3 6.6 26.6 0
Percent
Protein Identity: N.A. N.A. N.A. 63.4 59.1 N.A.
Protein Similarity: N.A. N.A. N.A. 76.6 72.5 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 0 0 0 7 0 13 32 0 13 0 0 7 % A
% Cys: 7 0 7 0 0 7 38 0 0 0 0 0 0 0 0 % C
% Asp: 7 0 0 7 7 38 7 0 0 13 7 7 0 0 13 % D
% Glu: 0 13 0 0 50 7 0 13 0 7 13 0 0 13 7 % E
% Phe: 0 0 0 44 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 13 0 0 7 7 0 0 7 0 0 7 0 0 0 7 % G
% His: 0 0 0 7 0 0 0 0 0 7 0 0 7 0 0 % H
% Ile: 7 38 13 13 7 7 7 7 7 7 0 7 32 0 0 % I
% Lys: 0 0 0 7 0 7 7 0 0 0 32 0 0 7 32 % K
% Leu: 7 13 13 7 7 13 13 7 13 7 0 7 25 50 7 % L
% Met: 0 7 7 0 0 0 0 7 0 7 0 0 0 7 0 % M
% Asn: 0 0 0 0 0 0 0 0 13 0 0 0 0 0 0 % N
% Pro: 0 7 7 0 0 0 13 0 0 0 13 7 0 0 0 % P
% Gln: 7 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % Q
% Arg: 0 7 44 0 7 7 0 7 7 7 13 7 7 7 19 % R
% Ser: 38 7 0 0 0 0 0 38 38 7 7 0 0 7 7 % S
% Thr: 0 0 0 0 7 0 7 7 0 7 0 44 13 0 0 % T
% Val: 7 7 0 0 7 13 0 7 7 0 0 0 13 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 7 0 0 7 0 0 0 0 0 0 7 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _