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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHX15
All Species:
24.24
Human Site:
S390
Identified Species:
35.56
UniProt:
O43143
Number Species:
15
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43143
NP_001349.2
795
90933
S390
I
K
I
I
P
L
Y
S
T
L
P
P
Q
Q
Q
Chimpanzee
Pan troglodytes
Q7YR39
1044
119631
A652
L
L
V
L
P
I
Y
A
N
L
P
S
D
M
Q
Rhesus Macaque
Macaca mulatta
XP_001106067
795
90884
S390
I
K
I
I
P
L
Y
S
T
L
P
P
Q
Q
Q
Dog
Lupus familis
XP_851535
795
91016
S390
I
K
I
I
P
L
Y
S
T
L
P
P
Q
Q
Q
Cat
Felis silvestris
Mouse
Mus musculus
O35286
795
90988
S390
I
K
I
I
P
L
Y
S
T
L
P
P
Q
Q
Q
Rat
Rattus norvegicus
Q5XI69
779
88496
K387
L
E
V
V
P
I
S
K
S
E
A
L
Q
R
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513650
820
93995
S415
I
K
I
I
P
L
Y
S
T
L
P
P
Q
Q
Q
Chicken
Gallus gallus
NP_001026330
762
87695
E369
Q
Q
Q
Q
R
I
F
E
P
P
P
P
K
K
Q
Frog
Xenopus laevis
Q5XH12
748
85094
N370
I
E
K
R
K
V
Y
N
T
R
I
R
A
E
S
Zebra Danio
Brachydanio rerio
NP_001108613
769
88372
S364
I
K
I
I
P
L
Y
S
T
L
P
P
Q
Q
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610269
729
82633
V351
G
A
I
G
R
K
V
V
V
S
T
N
I
A
E
Honey Bee
Apis mellifera
XP_392081
718
81782
I352
I
A
E
T
S
L
T
I
D
G
V
V
F
V
I
Nematode Worm
Caenorhab. elegans
Q20875
739
84370
N351
I
F
E
P
A
P
P
N
R
P
N
G
A
I
S
Sea Urchin
Strong. purpuratus
O17438
455
51461
E94
V
E
I
F
Y
T
P
E
P
E
R
D
Y
L
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O22899
729
82635
T352
G
R
K
I
V
V
S
T
N
I
A
E
T
S
L
Baker's Yeast
Sacchar. cerevisiae
P53131
767
87543
E358
H
Q
Q
Q
R
I
F
E
P
A
P
E
S
H
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
37.1
99.8
99.7
N.A.
99.6
39.2
N.A.
85.9
92.4
37.8
89
N.A.
71.6
74.3
68.5
50.6
Protein Similarity:
100
51.1
99.8
99.7
N.A.
99.7
57.1
N.A.
87.3
94.8
57.3
93.5
N.A.
81.8
82.6
78.8
54
P-Site Identity:
100
33.3
100
100
N.A.
100
13.3
N.A.
100
20
20
100
N.A.
6.6
13.3
6.6
6.6
P-Site Similarity:
100
66.6
100
100
N.A.
100
60
N.A.
100
53.3
46.6
100
N.A.
13.3
13.3
13.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
63.4
59.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
76.6
72.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
13
0
0
7
0
0
7
0
7
13
0
13
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
7
0
0
7
7
0
0
% D
% Glu:
0
19
13
0
0
0
0
19
0
13
0
13
0
7
13
% E
% Phe:
0
7
0
7
0
0
13
0
0
0
0
0
7
0
0
% F
% Gly:
13
0
0
7
0
0
0
0
0
7
0
7
0
0
0
% G
% His:
7
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% H
% Ile:
57
0
50
44
0
25
0
7
0
7
7
0
7
7
7
% I
% Lys:
0
38
13
0
7
7
0
7
0
0
0
0
7
7
0
% K
% Leu:
13
7
0
7
0
44
0
0
0
44
0
7
0
7
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% M
% Asn:
0
0
0
0
0
0
0
13
13
0
7
7
0
0
7
% N
% Pro:
0
0
0
7
50
7
13
0
19
13
57
44
0
0
0
% P
% Gln:
7
13
13
13
0
0
0
0
0
0
0
0
44
38
50
% Q
% Arg:
0
7
0
7
19
0
0
0
7
7
7
7
0
7
0
% R
% Ser:
0
0
0
0
7
0
13
38
7
7
0
7
7
7
19
% S
% Thr:
0
0
0
7
0
7
7
7
44
0
7
0
7
0
0
% T
% Val:
7
0
13
7
7
13
7
7
7
0
7
7
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
7
0
50
0
0
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _