KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHX15
All Species:
39.09
Human Site:
S677
Identified Species:
57.33
UniProt:
O43143
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43143
NP_001349.2
795
90933
S677
R
F
N
L
P
R
R
S
T
D
F
T
S
R
D
Chimpanzee
Pan troglodytes
Q7YR39
1044
119631
V930
G
L
L
E
R
V
E
V
G
L
S
S
C
Q
G
Rhesus Macaque
Macaca mulatta
XP_001106067
795
90884
S677
R
F
N
L
P
R
R
S
T
D
F
T
S
R
D
Dog
Lupus familis
XP_851535
795
91016
S677
R
F
N
L
P
R
R
S
T
D
F
T
S
R
D
Cat
Felis silvestris
Mouse
Mus musculus
O35286
795
90988
S677
R
F
N
L
P
R
R
S
T
D
F
T
S
R
D
Rat
Rattus norvegicus
Q5XI69
779
88496
E666
H
E
Q
E
T
K
L
E
W
I
I
F
H
E
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513650
820
93995
S702
R
F
N
L
P
R
R
S
T
D
F
T
S
R
D
Chicken
Gallus gallus
NP_001026330
762
87695
S644
R
F
N
L
P
R
R
S
T
D
F
T
S
R
D
Frog
Xenopus laevis
Q5XH12
748
85094
R632
G
Y
F
M
Q
I
A
R
D
V
D
G
L
G
N
Zebra Danio
Brachydanio rerio
NP_001108613
769
88372
S651
R
F
N
L
P
R
R
S
T
E
F
T
S
R
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610269
729
82633
S610
R
F
N
L
R
R
T
S
T
E
F
T
S
K
D
Honey Bee
Apis mellifera
XP_392081
718
81782
K605
T
S
T
E
F
T
S
K
D
Y
Y
I
N
I
R
Nematode Worm
Caenorhab. elegans
Q20875
739
84370
S621
K
Y
N
L
R
R
V
S
T
D
F
K
S
R
D
Sea Urchin
Strong. purpuratus
O17438
455
51461
V343
D
P
Q
L
A
K
M
V
I
A
S
T
D
Y
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O22899
729
82635
S608
R
F
N
L
K
M
C
S
T
D
F
N
S
R
D
Baker's Yeast
Sacchar. cerevisiae
P53131
767
87543
T637
Y
N
L
E
L
N
T
T
D
Y
E
S
P
K
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
37.1
99.8
99.7
N.A.
99.6
39.2
N.A.
85.9
92.4
37.8
89
N.A.
71.6
74.3
68.5
50.6
Protein Similarity:
100
51.1
99.8
99.7
N.A.
99.7
57.1
N.A.
87.3
94.8
57.3
93.5
N.A.
81.8
82.6
78.8
54
P-Site Identity:
100
0
100
100
N.A.
100
0
N.A.
100
100
0
93.3
N.A.
73.3
0
66.6
13.3
P-Site Similarity:
100
13.3
100
100
N.A.
100
6.6
N.A.
100
100
20
100
N.A.
86.6
13.3
80
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
63.4
59.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
76.6
72.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
73.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
73.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
7
0
7
0
0
7
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
7
0
0
0
0
0
7
0
0
% C
% Asp:
7
0
0
0
0
0
0
0
19
50
7
0
7
0
63
% D
% Glu:
0
7
0
25
0
0
7
7
0
13
7
0
0
7
0
% E
% Phe:
0
57
7
0
7
0
0
0
0
0
63
7
0
0
0
% F
% Gly:
13
0
0
0
0
0
0
0
7
0
0
7
0
7
7
% G
% His:
7
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% H
% Ile:
0
0
0
0
0
7
0
0
7
7
7
7
0
7
0
% I
% Lys:
7
0
0
0
7
13
0
7
0
0
0
7
0
13
0
% K
% Leu:
0
7
13
69
7
0
7
0
0
7
0
0
7
0
0
% L
% Met:
0
0
0
7
0
7
7
0
0
0
0
0
0
0
0
% M
% Asn:
0
7
63
0
0
7
0
0
0
0
0
7
7
0
7
% N
% Pro:
0
7
0
0
44
0
0
0
0
0
0
0
7
0
0
% P
% Gln:
0
0
13
0
7
0
0
0
0
0
0
0
0
7
0
% Q
% Arg:
57
0
0
0
19
57
44
7
0
0
0
0
0
57
7
% R
% Ser:
0
7
0
0
0
0
7
63
0
0
13
13
63
0
7
% S
% Thr:
7
0
7
0
7
7
13
7
63
0
0
57
0
0
0
% T
% Val:
0
0
0
0
0
7
7
13
0
7
0
0
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% W
% Tyr:
7
13
0
0
0
0
0
0
0
13
7
0
0
7
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _