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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHX15
All Species:
24.55
Human Site:
T231
Identified Species:
36
UniProt:
O43143
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43143
NP_001349.2
795
90933
T231
E
D
C
S
S
A
K
T
I
L
K
Y
M
T
D
Chimpanzee
Pan troglodytes
Q7YR39
1044
119631
T494
E
D
C
T
S
E
R
T
V
L
R
Y
M
T
D
Rhesus Macaque
Macaca mulatta
XP_001106067
795
90884
T231
E
D
C
S
S
A
K
T
I
L
K
Y
M
T
D
Dog
Lupus familis
XP_851535
795
91016
T231
E
D
C
S
S
A
K
T
I
L
K
Y
M
T
D
Cat
Felis silvestris
Mouse
Mus musculus
O35286
795
90988
T231
E
D
C
S
S
A
K
T
I
L
K
Y
M
T
D
Rat
Rattus norvegicus
Q5XI69
779
88496
P236
D
I
P
G
R
L
Y
P
V
R
E
K
F
C
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513650
820
93995
T256
E
D
C
S
S
A
K
T
I
L
K
Y
M
T
D
Chicken
Gallus gallus
NP_001026330
762
87695
A229
G
V
I
I
L
D
E
A
H
E
R
T
L
A
T
Frog
Xenopus laevis
Q5XH12
748
85094
T226
T
C
P
S
L
S
G
T
L
V
S
Y
Y
G
N
Zebra Danio
Brachydanio rerio
NP_001108613
769
88372
L224
R
E
A
M
N
D
P
L
L
E
R
Y
G
V
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610269
729
82633
Q215
V
L
K
E
V
I
R
Q
R
S
D
L
K
L
V
Honey Bee
Apis mellifera
XP_392081
718
81782
A215
L
K
L
V
I
M
S
A
T
L
D
A
G
K
F
Nematode Worm
Caenorhab. elegans
Q20875
739
84370
I215
E
R
T
L
A
T
D
I
L
M
G
L
I
K
E
Sea Urchin
Strong. purpuratus
O17438
455
51461
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O22899
729
82635
D216
E
V
L
R
N
R
P
D
L
K
L
V
V
M
S
Baker's Yeast
Sacchar. cerevisiae
P53131
767
87543
R220
I
L
D
E
A
H
E
R
T
L
A
T
D
I
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
37.1
99.8
99.7
N.A.
99.6
39.2
N.A.
85.9
92.4
37.8
89
N.A.
71.6
74.3
68.5
50.6
Protein Similarity:
100
51.1
99.8
99.7
N.A.
99.7
57.1
N.A.
87.3
94.8
57.3
93.5
N.A.
81.8
82.6
78.8
54
P-Site Identity:
100
66.6
100
100
N.A.
100
0
N.A.
100
0
20
6.6
N.A.
0
6.6
6.6
0
P-Site Similarity:
100
93.3
100
100
N.A.
100
26.6
N.A.
100
20
46.6
33.3
N.A.
6.6
6.6
40
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
63.4
59.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
76.6
72.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
13
32
0
13
0
0
7
7
0
7
0
% A
% Cys:
0
7
38
0
0
0
0
0
0
0
0
0
0
7
0
% C
% Asp:
7
38
7
0
0
13
7
7
0
0
13
0
7
0
38
% D
% Glu:
50
7
0
13
0
7
13
0
0
13
7
0
0
0
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
7
% F
% Gly:
7
0
0
7
0
0
7
0
0
0
7
0
13
7
0
% G
% His:
0
0
0
0
0
7
0
0
7
0
0
0
0
0
0
% H
% Ile:
7
7
7
7
7
7
0
7
32
0
0
0
7
7
7
% I
% Lys:
0
7
7
0
0
0
32
0
0
7
32
7
7
13
0
% K
% Leu:
7
13
13
7
13
7
0
7
25
50
7
13
7
7
7
% L
% Met:
0
0
0
7
0
7
0
0
0
7
0
0
38
7
0
% M
% Asn:
0
0
0
0
13
0
0
0
0
0
0
0
0
0
13
% N
% Pro:
0
0
13
0
0
0
13
7
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% Q
% Arg:
7
7
0
7
7
7
13
7
7
7
19
0
0
0
0
% R
% Ser:
0
0
0
38
38
7
7
0
0
7
7
0
0
0
7
% S
% Thr:
7
0
7
7
0
7
0
44
13
0
0
13
0
38
7
% T
% Val:
7
13
0
7
7
0
0
0
13
7
0
7
7
7
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
7
0
0
0
0
50
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _