Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DHX15 All Species: 31.21
Human Site: T604 Identified Species: 45.78
UniProt: O43143 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43143 NP_001349.2 795 90933 T604 P Q C F V R P T E A K K A A D
Chimpanzee Pan troglodytes Q7YR39 1044 119631 P860 N N S I F Y R P K D K V V H A
Rhesus Macaque Macaca mulatta XP_001106067 795 90884 T604 P Q C F V R P T E A K K A A D
Dog Lupus familis XP_851535 795 91016 T604 P Q C F V R P T E A K K A A D
Cat Felis silvestris
Mouse Mus musculus O35286 795 90988 T604 P Q C F V R P T E A K K A A D
Rat Rattus norvegicus Q5XI69 779 88496 R598 A Q L R E L I R K L K Q Q S D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513650 820 93995 T629 P Q C F V R P T E A K K A A D
Chicken Gallus gallus NP_001026330 762 87695 T571 P Q C F V R P T E A K K A A D
Frog Xenopus laevis Q5XH12 748 85094 N563 Y E Q M K R N N A S Q Y D V E
Zebra Danio Brachydanio rerio NP_001108613 769 88372 T578 P Q C F V R P T E A K K A A D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610269 729 82633 N537 P Q C F V R P N E A K K A A D
Honey Bee Apis mellifera XP_392081 718 81782 R538 A A D D A K M R F A H I D G D
Nematode Worm Caenorhab. elegans Q20875 739 84370 N548 P Q C W V R P N E M R T E A D
Sea Urchin Strong. purpuratus O17438 455 51461 T277 I L R S N L G T V V L Q L K K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O22899 729 82635 R535 P N C F V R P R E A Q K A A D
Baker's Yeast Sacchar. cerevisiae P53131 767 87543 T559 P N V F I R P T K D K K R A D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 37.1 99.8 99.7 N.A. 99.6 39.2 N.A. 85.9 92.4 37.8 89 N.A. 71.6 74.3 68.5 50.6
Protein Similarity: 100 51.1 99.8 99.7 N.A. 99.7 57.1 N.A. 87.3 94.8 57.3 93.5 N.A. 81.8 82.6 78.8 54
P-Site Identity: 100 6.6 100 100 N.A. 100 20 N.A. 100 100 6.6 100 N.A. 93.3 13.3 60 6.6
P-Site Similarity: 100 13.3 100 100 N.A. 100 40 N.A. 100 100 33.3 100 N.A. 93.3 20 73.3 13.3
Percent
Protein Identity: N.A. N.A. N.A. 63.4 59.1 N.A.
Protein Similarity: N.A. N.A. N.A. 76.6 72.5 N.A.
P-Site Identity: N.A. N.A. N.A. 80 60 N.A.
P-Site Similarity: N.A. N.A. N.A. 86.6 73.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 13 7 0 0 7 0 0 0 7 63 0 0 57 69 7 % A
% Cys: 0 0 63 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 7 7 0 0 0 0 0 13 0 0 13 0 82 % D
% Glu: 0 7 0 0 7 0 0 0 63 0 0 0 7 0 7 % E
% Phe: 0 0 0 63 7 0 0 0 7 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 7 0 0 0 0 0 0 7 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 7 0 0 7 0 % H
% Ile: 7 0 0 7 7 0 7 0 0 0 0 7 0 0 0 % I
% Lys: 0 0 0 0 7 7 0 0 19 0 69 63 0 7 7 % K
% Leu: 0 7 7 0 0 13 0 0 0 7 7 0 7 0 0 % L
% Met: 0 0 0 7 0 0 7 0 0 7 0 0 0 0 0 % M
% Asn: 7 19 0 0 7 0 7 19 0 0 0 0 0 0 0 % N
% Pro: 69 0 0 0 0 0 69 7 0 0 0 0 0 0 0 % P
% Gln: 0 63 7 0 0 0 0 0 0 0 13 13 7 0 0 % Q
% Arg: 0 0 7 7 0 75 7 19 0 0 7 0 7 0 0 % R
% Ser: 0 0 7 7 0 0 0 0 0 7 0 0 0 7 0 % S
% Thr: 0 0 0 0 0 0 0 57 0 0 0 7 0 0 0 % T
% Val: 0 0 7 0 63 0 0 0 7 7 0 7 7 7 0 % V
% Trp: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 7 0 0 0 0 7 0 0 0 0 0 7 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _