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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHX15
All Species:
18.18
Human Site:
Y127
Identified Species:
26.67
UniProt:
O43143
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43143
NP_001349.2
795
90933
Y127
N
L
P
H
T
P
R
Y
Y
D
I
L
K
K
R
Chimpanzee
Pan troglodytes
Q7YR39
1044
119631
K392
T
S
T
Q
A
Q
Q
K
E
S
I
Q
A
V
R
Rhesus Macaque
Macaca mulatta
XP_001106067
795
90884
Y127
N
L
P
H
T
P
R
Y
Y
D
I
L
K
K
R
Dog
Lupus familis
XP_851535
795
91016
Y127
N
L
P
H
T
P
R
Y
Y
D
I
L
K
K
R
Cat
Felis silvestris
Mouse
Mus musculus
O35286
795
90988
Y127
N
L
P
H
T
P
R
Y
Y
D
I
L
K
K
R
Rat
Rattus norvegicus
Q5XI69
779
88496
G131
C
T
L
G
S
K
V
G
Y
Q
V
R
F
D
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513650
820
93995
Y152
N
L
P
H
T
P
R
Y
Y
D
I
L
K
K
R
Chicken
Gallus gallus
NP_001026330
762
87695
F123
I
L
I
R
H
Q
S
F
V
L
V
G
E
T
G
Frog
Xenopus laevis
Q5XH12
748
85094
V116
H
Y
Q
H
G
A
V
V
C
T
Q
A
H
K
Q
Zebra Danio
Brachydanio rerio
NP_001108613
769
88372
N121
W
E
Y
K
E
R
F
N
D
I
L
N
R
H
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610269
729
82633
S115
W
C
V
D
F
A
V
S
K
G
R
K
G
V
S
Honey Bee
Apis mellifera
XP_392081
718
81782
P115
K
G
V
A
C
T
Q
P
R
R
V
A
A
M
S
Nematode Worm
Caenorhab. elegans
Q20875
739
84370
E115
Q
I
P
Q
W
A
V
E
F
M
K
Q
Q
Q
Q
Sea Urchin
Strong. purpuratus
O17438
455
51461
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O22899
729
82635
K116
D
N
S
D
K
G
R
K
W
L
V
G
C
T
Q
Baker's Yeast
Sacchar. cerevisiae
P53131
767
87543
G119
M
V
F
V
G
E
T
G
S
G
K
T
T
Q
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
37.1
99.8
99.7
N.A.
99.6
39.2
N.A.
85.9
92.4
37.8
89
N.A.
71.6
74.3
68.5
50.6
Protein Similarity:
100
51.1
99.8
99.7
N.A.
99.7
57.1
N.A.
87.3
94.8
57.3
93.5
N.A.
81.8
82.6
78.8
54
P-Site Identity:
100
13.3
100
100
N.A.
100
6.6
N.A.
100
6.6
13.3
0
N.A.
0
0
6.6
0
P-Site Similarity:
100
20
100
100
N.A.
100
20
N.A.
100
26.6
26.6
20
N.A.
0
13.3
40
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
63.4
59.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
76.6
72.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
7
19
0
0
0
0
0
13
13
0
0
% A
% Cys:
7
7
0
0
7
0
0
0
7
0
0
0
7
0
0
% C
% Asp:
7
0
0
13
0
0
0
0
7
32
0
0
0
7
7
% D
% Glu:
0
7
0
0
7
7
0
7
7
0
0
0
7
0
0
% E
% Phe:
0
0
7
0
7
0
7
7
7
0
0
0
7
0
0
% F
% Gly:
0
7
0
7
13
7
0
13
0
13
0
13
7
0
7
% G
% His:
7
0
0
38
7
0
0
0
0
0
0
0
7
7
0
% H
% Ile:
7
7
7
0
0
0
0
0
0
7
38
0
0
0
7
% I
% Lys:
7
0
0
7
7
7
0
13
7
0
13
7
32
38
0
% K
% Leu:
0
38
7
0
0
0
0
0
0
13
7
32
0
0
0
% L
% Met:
7
0
0
0
0
0
0
0
0
7
0
0
0
7
0
% M
% Asn:
32
7
0
0
0
0
0
7
0
0
0
7
0
0
0
% N
% Pro:
0
0
38
0
0
32
0
7
0
0
0
0
0
0
0
% P
% Gln:
7
0
7
13
0
13
13
0
0
7
7
13
7
13
25
% Q
% Arg:
0
0
0
7
0
7
38
0
7
7
7
7
7
0
38
% R
% Ser:
0
7
7
0
7
0
7
7
7
7
0
0
0
0
13
% S
% Thr:
7
7
7
0
32
7
7
0
0
7
0
7
7
13
0
% T
% Val:
0
7
13
7
0
0
25
7
7
0
25
0
0
13
0
% V
% Trp:
13
0
0
0
7
0
0
0
7
0
0
0
0
0
0
% W
% Tyr:
0
7
7
0
0
0
0
32
38
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _