Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DHX15 All Species: 18.79
Human Site: Y13 Identified Species: 27.56
UniProt: O43143 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43143 NP_001349.2 795 90933 Y13 R L D L G E D Y P S G K K R A
Chimpanzee Pan troglodytes Q7YR39 1044 119631 E105 R L L E D S E E S S E E T V S
Rhesus Macaque Macaca mulatta XP_001106067 795 90884 Y13 R L D L G E D Y P S G K K R A
Dog Lupus familis XP_851535 795 91016 Y13 R L D L E E D Y P S G K K R A
Cat Felis silvestris
Mouse Mus musculus O35286 795 90988 Y13 R L D L G E D Y P S G K K R A
Rat Rattus norvegicus Q5XI69 779 88496 R28 P V E L Q E E R P S A V R I A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513650 820 93995 R15 L L T V S L S R P F V P S V A
Chicken Gallus gallus NP_001026330 762 87695 Y13 R L D L G D D Y S S S K K R S
Frog Xenopus laevis Q5XH12 748 85094 E14 A Y E Q D I D E L I S D E K S
Zebra Danio Brachydanio rerio NP_001108613 769 88372 S14 L D L G D E Y S S S K K R S S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610269 729 82633 G13 I E V G E T Y G S K A K K D P
Honey Bee Apis mellifera XP_392081 718 81782 I13 I E V V D P Y I K R K A D G S
Nematode Worm Caenorhab. elegans Q20875 739 84370 G13 R L D L D G S G R G D R R R S
Sea Urchin Strong. purpuratus O17438 455 51461
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O22899 729 82635 V14 R K V S L F D V M E D P S L S
Baker's Yeast Sacchar. cerevisiae P53131 767 87543 P14 F S S E H P D P V E T S I P E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 37.1 99.8 99.7 N.A. 99.6 39.2 N.A. 85.9 92.4 37.8 89 N.A. 71.6 74.3 68.5 50.6
Protein Similarity: 100 51.1 99.8 99.7 N.A. 99.7 57.1 N.A. 87.3 94.8 57.3 93.5 N.A. 81.8 82.6 78.8 54
P-Site Identity: 100 20 100 93.3 N.A. 100 33.3 N.A. 20 73.3 6.6 20 N.A. 13.3 0 33.3 0
P-Site Similarity: 100 40 100 93.3 N.A. 100 60 N.A. 26.6 86.6 33.3 33.3 N.A. 13.3 13.3 53.3 0
Percent
Protein Identity: N.A. N.A. N.A. 63.4 59.1 N.A.
Protein Similarity: N.A. N.A. N.A. 76.6 72.5 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 0 0 0 0 0 0 0 0 13 7 0 0 38 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 7 38 0 32 7 50 0 0 0 13 7 7 7 0 % D
% Glu: 0 13 13 13 13 38 13 13 0 13 7 7 7 0 7 % E
% Phe: 7 0 0 0 0 7 0 0 0 7 0 0 0 0 0 % F
% Gly: 0 0 0 13 25 7 0 13 0 7 25 0 0 7 0 % G
% His: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 13 0 0 0 0 7 0 7 0 7 0 0 7 7 0 % I
% Lys: 0 7 0 0 0 0 0 0 7 7 13 44 38 7 0 % K
% Leu: 13 50 13 44 7 7 0 0 7 0 0 0 0 7 0 % L
% Met: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 7 0 0 0 0 13 0 7 38 0 0 13 0 7 7 % P
% Gln: 0 0 0 7 7 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 50 0 0 0 0 0 0 13 7 7 0 7 19 38 0 % R
% Ser: 0 7 7 7 7 7 13 7 25 50 13 7 13 7 44 % S
% Thr: 0 0 7 0 0 7 0 0 0 0 7 0 7 0 0 % T
% Val: 0 7 19 13 0 0 0 7 7 0 7 7 0 13 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 7 0 0 0 0 19 32 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _