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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHX15
All Species:
20.3
Human Site:
Y177
Identified Species:
29.78
UniProt:
O43143
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43143
NP_001349.2
795
90933
Y177
I
P
Q
W
C
V
E
Y
M
R
S
L
P
G
P
Chimpanzee
Pan troglodytes
Q7YR39
1044
119631
E442
I
P
Q
Y
L
F
E
E
G
Y
T
N
K
G
M
Rhesus Macaque
Macaca mulatta
XP_001106067
795
90884
Y177
I
P
Q
W
C
V
E
Y
M
R
S
L
P
G
P
Dog
Lupus familis
XP_851535
795
91016
Y177
I
P
Q
W
C
V
E
Y
M
R
S
L
P
G
P
Cat
Felis silvestris
Mouse
Mus musculus
O35286
795
90988
Y177
I
P
Q
W
C
V
E
Y
M
R
S
L
P
G
P
Rat
Rattus norvegicus
Q5XI69
779
88496
T181
E
A
H
E
R
T
L
T
T
D
I
L
F
G
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513650
820
93995
Y202
I
P
Q
W
C
V
E
Y
M
R
S
L
P
G
P
Chicken
Gallus gallus
NP_001026330
762
87695
A173
M
S
V
A
Q
R
V
A
D
E
M
D
V
M
L
Frog
Xenopus laevis
Q5XH12
748
85094
E166
I
L
R
Y
C
T
D
E
M
L
R
R
E
M
M
Zebra Danio
Brachydanio rerio
NP_001108613
769
88372
A171
C
T
Q
P
R
R
V
A
A
M
S
V
A
Q
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610269
729
82633
L165
D
C
S
T
A
K
T
L
L
K
Y
M
T
D
G
Honey Bee
Apis mellifera
XP_392081
718
81782
R165
M
T
D
G
M
L
L
R
E
G
M
S
D
P
M
Nematode Worm
Caenorhab. elegans
Q20875
739
84370
I165
G
Q
E
V
G
Y
S
I
R
F
E
D
C
I
S
Sea Urchin
Strong. purpuratus
O17438
455
51461
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O22899
729
82635
Y166
S
S
R
T
M
L
K
Y
L
T
D
G
M
L
L
Baker's Yeast
Sacchar. cerevisiae
P53131
767
87543
G169
E
E
M
D
V
K
L
G
E
E
V
G
Y
S
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
37.1
99.8
99.7
N.A.
99.6
39.2
N.A.
85.9
92.4
37.8
89
N.A.
71.6
74.3
68.5
50.6
Protein Similarity:
100
51.1
99.8
99.7
N.A.
99.7
57.1
N.A.
87.3
94.8
57.3
93.5
N.A.
81.8
82.6
78.8
54
P-Site Identity:
100
33.3
100
100
N.A.
100
13.3
N.A.
100
0
20
13.3
N.A.
0
0
0
0
P-Site Similarity:
100
46.6
100
100
N.A.
100
13.3
N.A.
100
6.6
40
20
N.A.
20
13.3
6.6
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
63.4
59.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
76.6
72.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
7
7
0
0
13
7
0
0
0
7
0
0
% A
% Cys:
7
7
0
0
38
0
0
0
0
0
0
0
7
0
0
% C
% Asp:
7
0
7
7
0
0
7
0
7
7
7
13
7
7
0
% D
% Glu:
13
7
7
7
0
0
38
13
13
13
7
0
7
0
0
% E
% Phe:
0
0
0
0
0
7
0
0
0
7
0
0
7
0
0
% F
% Gly:
7
0
0
7
7
0
0
7
7
7
0
13
0
44
7
% G
% His:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
44
0
0
0
0
0
0
7
0
0
7
0
0
7
7
% I
% Lys:
0
0
0
0
0
13
7
0
0
7
0
0
7
0
0
% K
% Leu:
0
7
0
0
7
13
19
7
13
7
0
38
0
7
19
% L
% Met:
13
0
7
0
13
0
0
0
38
7
13
7
7
13
19
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% N
% Pro:
0
38
0
7
0
0
0
0
0
0
0
0
32
7
32
% P
% Gln:
0
7
44
0
7
0
0
0
0
0
0
0
0
7
0
% Q
% Arg:
0
0
13
0
13
13
0
7
7
32
7
7
0
0
7
% R
% Ser:
7
13
7
0
0
0
7
0
0
0
38
7
0
7
7
% S
% Thr:
0
13
0
13
0
13
7
7
7
7
7
0
7
0
0
% T
% Val:
0
0
7
7
7
32
13
0
0
0
7
7
7
0
0
% V
% Trp:
0
0
0
32
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
13
0
7
0
38
0
7
7
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _