KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHX15
All Species:
25.15
Human Site:
Y254
Identified Species:
36.89
UniProt:
O43143
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43143
NP_001349.2
795
90933
Y254
N
D
P
L
L
E
R
Y
G
V
I
I
L
D
E
Chimpanzee
Pan troglodytes
Q7YR39
1044
119631
Y517
S
E
P
D
L
A
S
Y
S
V
V
M
V
D
E
Rhesus Macaque
Macaca mulatta
XP_001106067
795
90884
Y254
N
D
P
L
L
E
R
Y
G
V
I
I
L
D
E
Dog
Lupus familis
XP_851535
795
91016
Y254
N
D
P
L
L
E
R
Y
G
V
I
I
L
D
E
Cat
Felis silvestris
Mouse
Mus musculus
O35286
795
90988
Y254
N
D
P
L
L
E
R
Y
G
V
I
I
L
D
E
Rat
Rattus norvegicus
Q5XI69
779
88496
A258
E
N
T
A
Y
I
Q
A
I
V
K
V
T
M
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513650
820
93995
Y279
N
D
P
L
L
E
R
Y
G
V
I
I
L
D
E
Chicken
Gallus gallus
NP_001026330
762
87695
A251
K
E
V
V
R
Q
R
A
D
L
K
V
I
V
M
Frog
Xenopus laevis
Q5XH12
748
85094
T251
S
V
E
S
V
Y
T
T
S
L
P
R
D
Y
F
Zebra Danio
Brachydanio rerio
NP_001108613
769
88372
L246
R
T
L
A
T
D
I
L
M
G
V
L
K
E
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610269
729
82633
Y236
D
A
G
K
F
Q
Q
Y
F
D
N
A
P
L
M
Honey Bee
Apis mellifera
XP_392081
718
81782
G236
A
P
L
M
N
V
P
G
R
T
H
P
V
E
I
Nematode Worm
Caenorhab. elegans
Q20875
739
84370
S236
D
I
K
V
V
I
M
S
A
T
L
D
A
G
K
Sea Urchin
Strong. purpuratus
O17438
455
51461
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O22899
729
82635
G237
K
F
Q
E
Y
F
S
G
A
P
L
M
K
V
P
Baker's Yeast
Sacchar. cerevisiae
P53131
767
87543
L241
V
V
K
R
R
P
D
L
K
I
I
I
M
S
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
37.1
99.8
99.7
N.A.
99.6
39.2
N.A.
85.9
92.4
37.8
89
N.A.
71.6
74.3
68.5
50.6
Protein Similarity:
100
51.1
99.8
99.7
N.A.
99.7
57.1
N.A.
87.3
94.8
57.3
93.5
N.A.
81.8
82.6
78.8
54
P-Site Identity:
100
40
100
100
N.A.
100
6.6
N.A.
100
6.6
0
0
N.A.
6.6
0
0
0
P-Site Similarity:
100
73.3
100
100
N.A.
100
33.3
N.A.
100
46.6
20
26.6
N.A.
26.6
20
33.3
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
63.4
59.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
76.6
72.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
0
13
0
7
0
13
13
0
0
7
7
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
13
32
0
7
0
7
7
0
7
7
0
7
7
38
7
% D
% Glu:
7
13
7
7
0
32
0
0
0
0
0
0
0
13
38
% E
% Phe:
0
7
0
0
7
7
0
0
7
0
0
0
0
0
7
% F
% Gly:
0
0
7
0
0
0
0
13
32
7
0
0
0
7
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% H
% Ile:
0
7
0
0
0
13
7
0
7
7
38
38
7
0
7
% I
% Lys:
13
0
13
7
0
0
0
0
7
0
13
0
13
0
7
% K
% Leu:
0
0
13
32
38
0
0
13
0
13
13
7
32
7
0
% L
% Met:
0
0
0
7
0
0
7
0
7
0
0
13
7
7
13
% M
% Asn:
32
7
0
0
7
0
0
0
0
0
7
0
0
0
0
% N
% Pro:
0
7
38
0
0
7
7
0
0
7
7
7
7
0
7
% P
% Gln:
0
0
7
0
0
13
13
0
0
0
0
0
0
0
0
% Q
% Arg:
7
0
0
7
13
0
38
0
7
0
0
7
0
0
0
% R
% Ser:
13
0
0
7
0
0
13
7
13
0
0
0
0
7
0
% S
% Thr:
0
7
7
0
7
0
7
7
0
13
0
0
7
0
0
% T
% Val:
7
13
7
13
13
7
0
0
0
44
13
13
13
13
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
13
7
0
44
0
0
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _