Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DHX15 All Species: 30
Human Site: Y697 Identified Species: 44
UniProt: O43143 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43143 NP_001349.2 795 90933 Y697 R K A L V T G Y F M Q V A H L
Chimpanzee Pan troglodytes Q7YR39 1044 119631 Y950 R K A I T A G Y F Y H T A R L
Rhesus Macaque Macaca mulatta XP_001106067 795 90884 Y697 R K A L V T G Y F M Q V A H L
Dog Lupus familis XP_851535 795 91016 Y697 R K A L V T G Y F M Q V A H L
Cat Felis silvestris
Mouse Mus musculus O35286 795 90988 Y697 R K A L V T G Y F M Q V A H L
Rat Rattus norvegicus Q5XI69 779 88496 P686 V Y A R I V C P I R Y E W V R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513650 820 93995 Y722 R K A L V T G Y F M Q V A H L
Chicken Gallus gallus NP_001026330 762 87695 Y664 R K A L V T G Y F M Q V A H L
Frog Xenopus laevis Q5XH12 748 85094 H652 H K Q V G Q L H P D S G F C N
Zebra Danio Brachydanio rerio NP_001108613 769 88372 F671 R R A L V T G F F M Q V A H L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610269 729 82633 F630 R K A L V Q G F F M Q V A H L
Honey Bee Apis mellifera XP_392081 718 81782 H625 G F F M Q V A H L E R T G H Y
Nematode Worm Caenorhab. elegans Q20875 739 84370 F641 R K A L V A G F F M Q V A H L
Sea Urchin Strong. purpuratus O17438 455 51461 S363 L S V T A M L S V P Q C F L R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O22899 729 82635 Y628 R K A M L A G Y F M Q V A H L
Baker's Yeast Sacchar. cerevisiae P53131 767 87543 F657 K A L A S G F F M Q V A K K R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 37.1 99.8 99.7 N.A. 99.6 39.2 N.A. 85.9 92.4 37.8 89 N.A. 71.6 74.3 68.5 50.6
Protein Similarity: 100 51.1 99.8 99.7 N.A. 99.7 57.1 N.A. 87.3 94.8 57.3 93.5 N.A. 81.8 82.6 78.8 54
P-Site Identity: 100 53.3 100 100 N.A. 100 6.6 N.A. 100 100 6.6 86.6 N.A. 86.6 6.6 86.6 6.6
P-Site Similarity: 100 60 100 100 N.A. 100 13.3 N.A. 100 100 20 100 N.A. 93.3 26.6 93.3 6.6
Percent
Protein Identity: N.A. N.A. N.A. 63.4 59.1 N.A.
Protein Similarity: N.A. N.A. N.A. 76.6 72.5 N.A.
P-Site Identity: N.A. N.A. N.A. 80 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 93.3 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 75 7 7 19 7 0 0 0 0 7 69 0 0 % A
% Cys: 0 0 0 0 0 0 7 0 0 0 0 7 0 7 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 7 0 7 0 0 0 % E
% Phe: 0 7 7 0 0 0 7 25 69 0 0 0 13 0 0 % F
% Gly: 7 0 0 0 7 7 69 0 0 0 0 7 7 0 0 % G
% His: 7 0 0 0 0 0 0 13 0 0 7 0 0 69 0 % H
% Ile: 0 0 0 7 7 0 0 0 7 0 0 0 0 0 0 % I
% Lys: 7 69 0 0 0 0 0 0 0 0 0 0 7 7 0 % K
% Leu: 7 0 7 57 7 0 13 0 7 0 0 0 0 7 69 % L
% Met: 0 0 0 13 0 7 0 0 7 63 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % N
% Pro: 0 0 0 0 0 0 0 7 7 7 0 0 0 0 0 % P
% Gln: 0 0 7 0 7 13 0 0 0 7 69 0 0 0 0 % Q
% Arg: 69 7 0 7 0 0 0 0 0 7 7 0 0 7 19 % R
% Ser: 0 7 0 0 7 0 0 7 0 0 7 0 0 0 0 % S
% Thr: 0 0 0 7 7 44 0 0 0 0 0 13 0 0 0 % T
% Val: 7 0 7 7 57 13 0 0 7 0 7 63 0 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % W
% Tyr: 0 7 0 0 0 0 0 50 0 7 7 0 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _