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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RNMT All Species: 10.3
Human Site: S117 Identified Species: 17.44
UniProt: O43148 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43148 NP_003790.1 476 54844 S117 E D V P K D K S S T G D G T Q
Chimpanzee Pan troglodytes XP_001171239 476 54873 S117 E D V P K D K S S T G D G T Q
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_533404 460 53118 S118 D D F P K D E S S T G D G T Q
Cat Felis silvestris
Mouse Mus musculus Q9D0L8 465 53273 P104 G D V S E D E P S L G R L N Q
Rat Rattus norvegicus Q5U2U7 461 52798 G102 E D E P S P G G L T E R K R K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519491 604 67589 A123 D D V Q G E A A S G D G E G T
Chicken Gallus gallus XP_419132 415 47522 N93 Q A V A A H Y N E L Q E V G L
Frog Xenopus laevis Q9I8S2 402 45985 Y80 G S L V V T H Y N E L P E T G
Zebra Danio Brachydanio rerio Q1MTD3 400 45942 N78 Q K V A T H Y N K I K E C G L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VJQ4 427 48660 K102 A G R K D R Q K S K I F F M R
Honey Bee Apis mellifera XP_395738 367 42655 H45 N T L L V V E H Y N S V E N K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785441 457 51312 G113 T V L D L C C G K G G D L L K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LHQ7 370 42219 Y47 A R K V A D H Y S R R T N Q T
Baker's Yeast Sacchar. cerevisiae P32783 436 50322 R105 L R E E Q L K R H E I E M T A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 N.A. 85.7 N.A. 74.7 76 N.A. 55.2 62.6 59.4 52.7 N.A. 39 38.8 N.A. 46
Protein Similarity: 100 99.3 N.A. 90.1 N.A. 84 84 N.A. 63.7 72 71.8 67.8 N.A. 58.8 54.2 N.A. 61.5
P-Site Identity: 100 100 N.A. 80 N.A. 40 26.6 N.A. 20 6.6 6.6 6.6 N.A. 6.6 0 N.A. 13.3
P-Site Similarity: 100 100 N.A. 93.3 N.A. 53.3 33.3 N.A. 40 26.6 20 26.6 N.A. 20 20 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. 28.7 29.4 N.A.
Protein Similarity: N.A. N.A. N.A. 43.2 47 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 15 8 0 15 15 0 8 8 0 0 0 0 0 0 8 % A
% Cys: 0 0 0 0 0 8 8 0 0 0 0 0 8 0 0 % C
% Asp: 15 43 0 8 8 36 0 0 0 0 8 29 0 0 0 % D
% Glu: 22 0 15 8 8 8 22 0 8 15 8 22 22 0 0 % E
% Phe: 0 0 8 0 0 0 0 0 0 0 0 8 8 0 0 % F
% Gly: 15 8 0 0 8 0 8 15 0 15 36 8 22 22 8 % G
% His: 0 0 0 0 0 15 15 8 8 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 8 15 0 0 0 0 % I
% Lys: 0 8 8 8 22 0 22 8 15 8 8 0 8 0 22 % K
% Leu: 8 0 22 8 8 8 0 0 8 15 8 0 15 8 15 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 8 8 0 % M
% Asn: 8 0 0 0 0 0 0 15 8 8 0 0 8 15 0 % N
% Pro: 0 0 0 29 0 8 0 8 0 0 0 8 0 0 0 % P
% Gln: 15 0 0 8 8 0 8 0 0 0 8 0 0 8 29 % Q
% Arg: 0 15 8 0 0 8 0 8 0 8 8 15 0 8 8 % R
% Ser: 0 8 0 8 8 0 0 22 50 0 8 0 0 0 0 % S
% Thr: 8 8 0 0 8 8 0 0 0 29 0 8 0 36 15 % T
% Val: 0 8 43 15 15 8 0 0 0 0 0 8 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 15 15 8 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _