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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RNMT All Species: 15.45
Human Site: S431 Identified Species: 26.15
UniProt: O43148 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43148 NP_003790.1 476 54844 S431 N E S S K L V S E K V D D Y E
Chimpanzee Pan troglodytes XP_001171239 476 54873 S431 N E S S K L V S E K V D D Y E
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_533404 460 53118 M417 N K M L L K R M Q A L E P Y P
Cat Felis silvestris
Mouse Mus musculus Q9D0L8 465 53273 S420 H E N S K L A S E K V G D Y T
Rat Rattus norvegicus Q5U2U7 461 52798 S416 N E N S K L A S E K A G D Y A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519491 604 67589 S440 N E H S K L V S D N M E D Y E
Chicken Gallus gallus XP_419132 415 47522 K372 D S R L A S D K P D D Y E H A
Frog Xenopus laevis Q9I8S2 402 45985 R359 N T K L V S G R T E D Y E H A
Zebra Danio Brachydanio rerio Q1MTD3 400 45942 G357 R G Q L S S S G P G E Y D H A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VJQ4 427 48660 Q384 V S N F Q G A Q R S R S V G T
Honey Bee Apis mellifera XP_395738 367 42655 G324 R N D V S L V G K P E D Y Q H
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785441 457 51312 E410 E E A A P V A E E K K E E E E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LHQ7 370 42219 W327 S T L S A D E W E A A Y L Y L
Baker's Yeast Sacchar. cerevisiae P32783 436 50322 R392 E R F S P K M R E G L Q R S D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 N.A. 85.7 N.A. 74.7 76 N.A. 55.2 62.6 59.4 52.7 N.A. 39 38.8 N.A. 46
Protein Similarity: 100 99.3 N.A. 90.1 N.A. 84 84 N.A. 63.7 72 71.8 67.8 N.A. 58.8 54.2 N.A. 61.5
P-Site Identity: 100 100 N.A. 13.3 N.A. 66.6 66.6 N.A. 66.6 0 6.6 6.6 N.A. 0 20 N.A. 26.6
P-Site Similarity: 100 100 N.A. 40 N.A. 80 73.3 N.A. 86.6 20 26.6 13.3 N.A. 13.3 26.6 N.A. 60
Percent
Protein Identity: N.A. N.A. N.A. 28.7 29.4 N.A.
Protein Similarity: N.A. N.A. N.A. 43.2 47 N.A.
P-Site Identity: N.A. N.A. N.A. 20 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 8 15 0 29 0 0 15 15 0 0 0 29 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 8 0 0 8 8 0 8 8 15 22 43 0 8 % D
% Glu: 15 43 0 0 0 0 8 8 50 8 15 22 22 8 29 % E
% Phe: 0 0 8 8 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 8 0 0 0 8 8 15 0 15 0 15 0 8 0 % G
% His: 8 0 8 0 0 0 0 0 0 0 0 0 0 22 8 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 8 8 0 36 15 0 8 8 36 8 0 0 0 0 % K
% Leu: 0 0 8 29 8 43 0 0 0 0 15 0 8 0 8 % L
% Met: 0 0 8 0 0 0 8 8 0 0 8 0 0 0 0 % M
% Asn: 43 8 22 0 0 0 0 0 0 8 0 0 0 0 0 % N
% Pro: 0 0 0 0 15 0 0 0 15 8 0 0 8 0 8 % P
% Gln: 0 0 8 0 8 0 0 8 8 0 0 8 0 8 0 % Q
% Arg: 15 8 8 0 0 0 8 15 8 0 8 0 8 0 0 % R
% Ser: 8 15 15 50 15 22 8 36 0 8 0 8 0 8 0 % S
% Thr: 0 15 0 0 0 0 0 0 8 0 0 0 0 0 15 % T
% Val: 8 0 0 8 8 8 29 0 0 0 22 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 29 8 50 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _