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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RNMT All Species: 11.52
Human Site: T109 Identified Species: 19.49
UniProt: O43148 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43148 NP_003790.1 476 54844 T109 S K K R K R E T E D V P K D K
Chimpanzee Pan troglodytes XP_001171239 476 54873 T109 S K K R K R E T E D V P K D K
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_533404 460 53118 T110 S R K R R M E T D D F P K D E
Cat Felis silvestris
Mouse Mus musculus Q9D0L8 465 53273 R96 A K R S K L E R G D V S E D E
Rat Rattus norvegicus Q5U2U7 461 52798 S94 K L E R G G G S E D E P S P G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519491 604 67589 G115 P Q K R K L E G D D V Q G E A
Chicken Gallus gallus XP_419132 415 47522 G85 V P S E A G H G Q A V A A H Y
Frog Xenopus laevis Q9I8S2 402 45985 H72 R P R L E E G H G S L V V T H
Zebra Danio Brachydanio rerio Q1MTD3 400 45942 S70 V T E D S L H S Q K V A T H Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VJQ4 427 48660 E94 H H Y N E L K E A G R K D R Q
Honey Bee Apis mellifera XP_395738 367 42655 D37 S S K K I H S D N T L L V V E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785441 457 51312 C105 A V H R K K G C T V L D L C C
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LHQ7 370 42219 F39 E D E T T K N F A R K V A D H
Baker's Yeast Sacchar. cerevisiae P32783 436 50322 K97 L R K Q R A Q K L R E E Q L K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 N.A. 85.7 N.A. 74.7 76 N.A. 55.2 62.6 59.4 52.7 N.A. 39 38.8 N.A. 46
Protein Similarity: 100 99.3 N.A. 90.1 N.A. 84 84 N.A. 63.7 72 71.8 67.8 N.A. 58.8 54.2 N.A. 61.5
P-Site Identity: 100 100 N.A. 60 N.A. 40 26.6 N.A. 40 6.6 0 6.6 N.A. 0 13.3 N.A. 13.3
P-Site Similarity: 100 100 N.A. 86.6 N.A. 66.6 40 N.A. 60 13.3 20 26.6 N.A. 20 33.3 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. 28.7 29.4 N.A.
Protein Similarity: N.A. N.A. N.A. 43.2 47 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 15 0 0 0 8 8 0 0 15 8 0 15 15 0 8 % A
% Cys: 0 0 0 0 0 0 0 8 0 0 0 0 0 8 8 % C
% Asp: 0 8 0 8 0 0 0 8 15 43 0 8 8 36 0 % D
% Glu: 8 0 22 8 15 8 36 8 22 0 15 8 8 8 22 % E
% Phe: 0 0 0 0 0 0 0 8 0 0 8 0 0 0 0 % F
% Gly: 0 0 0 0 8 15 22 15 15 8 0 0 8 0 8 % G
% His: 8 8 8 0 0 8 15 8 0 0 0 0 0 15 15 % H
% Ile: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 8 22 43 8 36 15 8 8 0 8 8 8 22 0 22 % K
% Leu: 8 8 0 8 0 29 0 0 8 0 22 8 8 8 0 % L
% Met: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 8 0 0 8 0 8 0 0 0 0 0 0 % N
% Pro: 8 15 0 0 0 0 0 0 0 0 0 29 0 8 0 % P
% Gln: 0 8 0 8 0 0 8 0 15 0 0 8 8 0 8 % Q
% Arg: 8 15 15 43 15 15 0 8 0 15 8 0 0 8 0 % R
% Ser: 29 8 8 8 8 0 8 15 0 8 0 8 8 0 0 % S
% Thr: 0 8 0 8 8 0 0 22 8 8 0 0 8 8 0 % T
% Val: 15 8 0 0 0 0 0 0 0 8 43 15 15 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 15 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _