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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIAA0406
All Species:
18.79
Human Site:
S453
Identified Species:
45.93
UniProt:
O43156
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43156
NP_055472.1
1089
122069
S453
V
E
E
R
R
W
N
S
D
D
L
N
A
S
P
Chimpanzee
Pan troglodytes
XP_514634
1089
121903
S453
V
E
E
R
R
W
N
S
D
D
L
N
A
S
P
Rhesus Macaque
Macaca mulatta
XP_001090176
1089
122101
S453
V
E
E
R
R
W
N
S
D
D
L
N
A
S
P
Dog
Lupus familis
XP_534416
1097
122026
N458
V
V
E
E
R
C
W
N
S
G
P
L
G
A
S
Cat
Felis silvestris
Mouse
Mus musculus
Q91V83
1085
120824
S453
V
E
E
R
R
W
N
S
D
N
L
S
A
S
A
Rat
Rattus norvegicus
NP_001128091
1088
121092
S453
V
E
E
R
R
W
N
S
D
N
L
S
A
S
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001234099
1094
120916
V452
E
D
R
R
W
G
C
V
G
G
Y
D
P
S
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_698602
1079
120278
E450
T
D
V
K
I
I
E
E
K
S
L
T
S
S
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120334
724
83764
K147
L
K
R
H
S
H
Y
K
V
R
K
E
L
V
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001199584
616
69630
Y38
L
L
L
M
N
V
D
Y
L
S
D
S
V
S
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
97
87.2
N.A.
84.7
84.9
N.A.
N.A.
60.9
N.A.
54.4
N.A.
N.A.
22.1
N.A.
22.6
Protein Similarity:
100
99.3
98.3
92.3
N.A.
91.8
92.5
N.A.
N.A.
77.1
N.A.
70.4
N.A.
N.A.
40.3
N.A.
34.1
P-Site Identity:
100
100
100
20
N.A.
80
80
N.A.
N.A.
13.3
N.A.
13.3
N.A.
N.A.
0
N.A.
6.6
P-Site Similarity:
100
100
100
33.3
N.A.
93.3
93.3
N.A.
N.A.
26.6
N.A.
33.3
N.A.
N.A.
13.3
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
50
10
40
% A
% Cys:
0
0
0
0
0
10
10
0
0
0
0
0
0
0
0
% C
% Asp:
0
20
0
0
0
0
10
0
50
30
10
10
0
0
0
% D
% Glu:
10
50
60
10
0
0
10
10
0
0
0
10
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
10
0
0
10
20
0
0
10
0
10
% G
% His:
0
0
0
10
0
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
10
10
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
10
0
10
0
0
0
10
10
0
10
0
0
0
0
% K
% Leu:
20
10
10
0
0
0
0
0
10
0
60
10
10
0
0
% L
% Met:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
50
10
0
20
0
30
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
10
0
10
0
30
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
20
60
60
0
0
0
0
10
0
0
0
0
0
% R
% Ser:
0
0
0
0
10
0
0
50
10
20
0
30
10
80
10
% S
% Thr:
10
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% T
% Val:
60
10
10
0
0
10
0
10
10
0
0
0
10
10
0
% V
% Trp:
0
0
0
0
10
50
10
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
10
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _