Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RRP8 All Species: 14.55
Human Site: S230 Identified Species: 32
UniProt: O43159 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43159 NP_056139.1 456 50715 S230 S P V P R T D S H E A R A G A
Chimpanzee Pan troglodytes XP_508260 495 54574 S269 P P V P R T D S H E A R A G A
Rhesus Macaque Macaca mulatta XP_001100895 484 53680 S258 P A V S R T D S H E A R A A D
Dog Lupus familis XP_534039 602 65995 N376 P P A P S P D N H E D R A G A
Cat Felis silvestris
Mouse Mus musculus Q9DB85 457 51048 S231 P P V P K S D S Q E S R A G A
Rat Rattus norvegicus Q5U4F0 457 51198 S231 P P A P K S D S Q E T R A G A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001334686 533 59654 A316 A P L D P S T A L R L K M E K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001120291 230 26918 E32 S R F R Y L N E T L Y N N E S
Nematode Worm Caenorhab. elegans NP_499920 343 39430 K145 R F R F L N E K L Y T C T G S
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002298548 220 24956 G22 E K L Y T C T G D E A L D Y F
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_198869 287 32742 G89 E K L Y T C S G K E A L D Y F
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91.5 88.4 61.9 N.A. 76.1 74.4 N.A. N.A. N.A. N.A. 34.7 N.A. N.A. 25.6 34.4 N.A.
Protein Similarity: 100 91.5 90 66.1 N.A. 83.8 82.7 N.A. N.A. N.A. N.A. 52.1 N.A. N.A. 36.6 51.7 N.A.
P-Site Identity: 100 93.3 66.6 60 N.A. 66.6 60 N.A. N.A. N.A. N.A. 6.6 N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: 100 93.3 66.6 66.6 N.A. 86.6 73.3 N.A. N.A. N.A. N.A. 40 N.A. N.A. 20 20 N.A.
Percent
Protein Identity: 25.8 N.A. N.A. 31.3 N.A. N.A.
Protein Similarity: 33.1 N.A. N.A. 42.5 N.A. N.A.
P-Site Identity: 13.3 N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: 20 N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 10 19 0 0 0 0 10 0 0 46 0 55 10 46 % A
% Cys: 0 0 0 0 0 19 0 0 0 0 0 10 0 0 0 % C
% Asp: 0 0 0 10 0 0 55 0 10 0 10 0 19 0 10 % D
% Glu: 19 0 0 0 0 0 10 10 0 73 0 0 0 19 0 % E
% Phe: 0 10 10 10 0 0 0 0 0 0 0 0 0 0 19 % F
% Gly: 0 0 0 0 0 0 0 19 0 0 0 0 0 55 0 % G
% His: 0 0 0 0 0 0 0 0 37 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 19 0 0 19 0 0 10 10 0 0 10 0 0 10 % K
% Leu: 0 0 28 0 10 10 0 0 19 10 10 19 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % M
% Asn: 0 0 0 0 0 10 10 10 0 0 0 10 10 0 0 % N
% Pro: 46 55 0 46 10 10 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 19 0 0 0 0 0 0 % Q
% Arg: 10 10 10 10 28 0 0 0 0 10 0 55 0 0 0 % R
% Ser: 19 0 0 10 10 28 10 46 0 0 10 0 0 0 19 % S
% Thr: 0 0 0 0 19 28 19 0 10 0 19 0 10 0 0 % T
% Val: 0 0 37 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 19 10 0 0 0 0 10 10 0 0 19 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _