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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RRP8
All Species:
23.03
Human Site:
S416
Identified Species:
50.67
UniProt:
O43159
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43159
NP_056139.1
456
50715
S416
K
L
G
F
K
I
V
S
K
D
L
T
N
S
H
Chimpanzee
Pan troglodytes
XP_508260
495
54574
S455
K
L
G
F
K
I
V
S
K
D
L
T
N
S
H
Rhesus Macaque
Macaca mulatta
XP_001100895
484
53680
S444
K
L
G
F
K
I
V
S
K
D
L
T
N
S
H
Dog
Lupus familis
XP_534039
602
65995
S562
K
L
G
F
K
V
I
S
K
D
L
T
N
S
H
Cat
Felis silvestris
Mouse
Mus musculus
Q9DB85
457
51048
Y417
K
L
G
F
K
I
I
Y
K
D
L
T
N
S
H
Rat
Rattus norvegicus
Q5U4F0
457
51198
Y417
K
L
G
F
K
V
I
Y
K
D
L
T
N
S
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001334686
533
59654
I493
L
S
N
M
G
F
K
I
V
N
K
D
T
E
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120291
230
26918
T191
N
S
Y
G
F
K
N
T
W
K
D
L
S
H
N
Nematode Worm
Caenorhab. elegans
NP_499920
343
39430
Q304
I
T
K
M
G
F
E
Q
S
H
R
R
E
L
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002298548
220
24956
L181
D
L
G
F
T
S
T
L
K
D
F
S
N
K
M
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_198869
287
32742
L248
D
L
G
F
T
S
V
L
K
D
F
S
N
K
M
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.5
88.4
61.9
N.A.
76.1
74.4
N.A.
N.A.
N.A.
N.A.
34.7
N.A.
N.A.
25.6
34.4
N.A.
Protein Similarity:
100
91.5
90
66.1
N.A.
83.8
82.7
N.A.
N.A.
N.A.
N.A.
52.1
N.A.
N.A.
36.6
51.7
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
86.6
80
N.A.
N.A.
N.A.
N.A.
0
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
20
0
N.A.
Percent
Protein Identity:
25.8
N.A.
N.A.
31.3
N.A.
N.A.
Protein Similarity:
33.1
N.A.
N.A.
42.5
N.A.
N.A.
P-Site Identity:
40
N.A.
N.A.
46.6
N.A.
N.A.
P-Site Similarity:
46.6
N.A.
N.A.
53.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
19
0
0
0
0
0
0
0
0
73
10
10
0
0
0
% D
% Glu:
0
0
0
0
0
0
10
0
0
0
0
0
10
10
0
% E
% Phe:
0
0
0
73
10
19
0
0
0
0
19
0
0
0
0
% F
% Gly:
0
0
73
10
19
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
10
0
0
0
10
55
% H
% Ile:
10
0
0
0
0
37
28
10
0
0
0
0
0
0
0
% I
% Lys:
55
0
10
0
55
10
10
0
73
10
10
0
0
19
0
% K
% Leu:
10
73
0
0
0
0
0
19
0
0
55
10
0
10
0
% L
% Met:
0
0
0
19
0
0
0
0
0
0
0
0
0
0
19
% M
% Asn:
10
0
10
0
0
0
10
0
0
10
0
0
73
0
19
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
10
10
0
0
0
% R
% Ser:
0
19
0
0
0
19
0
37
10
0
0
19
10
55
0
% S
% Thr:
0
10
0
0
19
0
10
10
0
0
0
55
10
0
10
% T
% Val:
0
0
0
0
0
19
37
0
10
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
19
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _