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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SIPA1L1
All Species:
13.64
Human Site:
S1181
Identified Species:
37.5
UniProt:
O43166
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43166
NP_056371.1
1804
200029
S1181
G
F
G
V
S
R
R
S
P
A
S
I
D
R
Q
Chimpanzee
Pan troglodytes
XP_510040
1804
199959
S1181
G
F
G
V
S
R
R
S
P
A
S
I
D
R
Q
Rhesus Macaque
Macaca mulatta
XP_001084201
1804
200030
S1181
G
F
G
V
S
R
R
S
P
A
S
I
D
R
Q
Dog
Lupus familis
XP_537502
1806
199834
S1182
G
F
G
V
S
R
R
S
P
A
S
I
D
R
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8C0T5
1782
197013
G1160
L
S
S
S
S
E
T
G
S
G
G
G
T
Y
R
Rat
Rattus norvegicus
O35412
1822
201906
G1199
L
S
S
S
S
E
T
G
S
G
G
G
T
Y
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZMV8
730
80773
F138
C
E
E
E
E
E
N
F
S
P
S
P
Y
G
Y
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A5PF44
1015
114125
D423
L
Y
Q
D
L
M
P
D
M
H
K
N
M
L
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785253
1625
180489
M1033
C
T
Q
T
H
E
E
M
I
D
L
L
R
T
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.5
96.9
N.A.
94.6
93.3
N.A.
N.A.
20.2
N.A.
21.1
N.A.
N.A.
N.A.
N.A.
32.6
Protein Similarity:
100
99.9
99.7
98.5
N.A.
97
95.7
N.A.
N.A.
28.6
N.A.
33.4
N.A.
N.A.
N.A.
N.A.
49.5
P-Site Identity:
100
100
100
100
N.A.
6.6
6.6
N.A.
N.A.
6.6
N.A.
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
13.3
13.3
N.A.
N.A.
6.6
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
45
0
0
0
0
0
% A
% Cys:
23
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
12
0
0
0
12
0
12
0
0
45
0
0
% D
% Glu:
0
12
12
12
12
45
12
0
0
0
0
0
0
0
0
% E
% Phe:
0
45
0
0
0
0
0
12
0
0
0
0
0
0
0
% F
% Gly:
45
0
45
0
0
0
0
23
0
23
23
23
0
12
0
% G
% His:
0
0
0
0
12
0
0
0
0
12
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
12
0
0
45
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% K
% Leu:
34
0
0
0
12
0
0
0
0
0
12
12
0
12
0
% L
% Met:
0
0
0
0
0
12
0
12
12
0
0
0
12
0
0
% M
% Asn:
0
0
0
0
0
0
12
0
0
0
0
12
0
0
12
% N
% Pro:
0
0
0
0
0
0
12
0
45
12
0
12
0
0
0
% P
% Gln:
0
0
23
0
0
0
0
0
0
0
0
0
0
0
45
% Q
% Arg:
0
0
0
0
0
45
45
0
0
0
0
0
12
45
23
% R
% Ser:
0
23
23
23
67
0
0
45
34
0
56
0
0
0
12
% S
% Thr:
0
12
0
12
0
0
23
0
0
0
0
0
23
12
0
% T
% Val:
0
0
0
45
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
12
0
0
0
0
0
0
0
0
0
0
12
23
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _