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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SIPA1L1 All Species: 13.64
Human Site: S1227 Identified Species: 37.5
UniProt: O43166 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.38
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43166 NP_056371.1 1804 200029 S1227 R G P Q D F N S F V L E Q H E
Chimpanzee Pan troglodytes XP_510040 1804 199959 S1227 R G P Q D F N S F V L E Q H E
Rhesus Macaque Macaca mulatta XP_001084201 1804 200030 S1227 R G P Q D F N S F V L E Q H E
Dog Lupus familis XP_537502 1806 199834 S1228 R G P Q D F N S F V L E Q H E
Cat Felis silvestris
Mouse Mus musculus Q8C0T5 1782 197013 R1206 K S T P S W Q R S E D S L A D
Rat Rattus norvegicus O35412 1822 201906 R1245 K S T P S W Q R S E D S L A D
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZMV8 730 80773 C184 N L I L S I K C E E V D G T E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A5PF44 1015 114125 V469 A L K L K T I V R G D A P T S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785253 1625 180489 R1079 V T Q P G G A R L G F N R G T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 99.5 96.9 N.A. 94.6 93.3 N.A. N.A. 20.2 N.A. 21.1 N.A. N.A. N.A. N.A. 32.6
Protein Similarity: 100 99.9 99.7 98.5 N.A. 97 95.7 N.A. N.A. 28.6 N.A. 33.4 N.A. N.A. N.A. N.A. 49.5
P-Site Identity: 100 100 100 100 N.A. 0 0 N.A. N.A. 6.6 N.A. 0 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 100 100 N.A. 20 20 N.A. N.A. 20 N.A. 0 N.A. N.A. N.A. N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 0 0 0 0 0 12 0 0 0 0 12 0 23 0 % A
% Cys: 0 0 0 0 0 0 0 12 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 45 0 0 0 0 0 34 12 0 0 23 % D
% Glu: 0 0 0 0 0 0 0 0 12 34 0 45 0 0 56 % E
% Phe: 0 0 0 0 0 45 0 0 45 0 12 0 0 0 0 % F
% Gly: 0 45 0 0 12 12 0 0 0 23 0 0 12 12 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 45 0 % H
% Ile: 0 0 12 0 0 12 12 0 0 0 0 0 0 0 0 % I
% Lys: 23 0 12 0 12 0 12 0 0 0 0 0 0 0 0 % K
% Leu: 0 23 0 23 0 0 0 0 12 0 45 0 23 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 12 0 0 0 0 0 45 0 0 0 0 12 0 0 0 % N
% Pro: 0 0 45 34 0 0 0 0 0 0 0 0 12 0 0 % P
% Gln: 0 0 12 45 0 0 23 0 0 0 0 0 45 0 0 % Q
% Arg: 45 0 0 0 0 0 0 34 12 0 0 0 12 0 0 % R
% Ser: 0 23 0 0 34 0 0 45 23 0 0 23 0 0 12 % S
% Thr: 0 12 23 0 0 12 0 0 0 0 0 0 0 23 12 % T
% Val: 12 0 0 0 0 0 0 12 0 45 12 0 0 0 0 % V
% Trp: 0 0 0 0 0 23 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _