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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SIPA1L1
All Species:
13.64
Human Site:
S1227
Identified Species:
37.5
UniProt:
O43166
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.38
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43166
NP_056371.1
1804
200029
S1227
R
G
P
Q
D
F
N
S
F
V
L
E
Q
H
E
Chimpanzee
Pan troglodytes
XP_510040
1804
199959
S1227
R
G
P
Q
D
F
N
S
F
V
L
E
Q
H
E
Rhesus Macaque
Macaca mulatta
XP_001084201
1804
200030
S1227
R
G
P
Q
D
F
N
S
F
V
L
E
Q
H
E
Dog
Lupus familis
XP_537502
1806
199834
S1228
R
G
P
Q
D
F
N
S
F
V
L
E
Q
H
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8C0T5
1782
197013
R1206
K
S
T
P
S
W
Q
R
S
E
D
S
L
A
D
Rat
Rattus norvegicus
O35412
1822
201906
R1245
K
S
T
P
S
W
Q
R
S
E
D
S
L
A
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZMV8
730
80773
C184
N
L
I
L
S
I
K
C
E
E
V
D
G
T
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A5PF44
1015
114125
V469
A
L
K
L
K
T
I
V
R
G
D
A
P
T
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785253
1625
180489
R1079
V
T
Q
P
G
G
A
R
L
G
F
N
R
G
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.5
96.9
N.A.
94.6
93.3
N.A.
N.A.
20.2
N.A.
21.1
N.A.
N.A.
N.A.
N.A.
32.6
Protein Similarity:
100
99.9
99.7
98.5
N.A.
97
95.7
N.A.
N.A.
28.6
N.A.
33.4
N.A.
N.A.
N.A.
N.A.
49.5
P-Site Identity:
100
100
100
100
N.A.
0
0
N.A.
N.A.
6.6
N.A.
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
20
20
N.A.
N.A.
20
N.A.
0
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
0
0
0
12
0
0
0
0
12
0
23
0
% A
% Cys:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
45
0
0
0
0
0
34
12
0
0
23
% D
% Glu:
0
0
0
0
0
0
0
0
12
34
0
45
0
0
56
% E
% Phe:
0
0
0
0
0
45
0
0
45
0
12
0
0
0
0
% F
% Gly:
0
45
0
0
12
12
0
0
0
23
0
0
12
12
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
45
0
% H
% Ile:
0
0
12
0
0
12
12
0
0
0
0
0
0
0
0
% I
% Lys:
23
0
12
0
12
0
12
0
0
0
0
0
0
0
0
% K
% Leu:
0
23
0
23
0
0
0
0
12
0
45
0
23
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
12
0
0
0
0
0
45
0
0
0
0
12
0
0
0
% N
% Pro:
0
0
45
34
0
0
0
0
0
0
0
0
12
0
0
% P
% Gln:
0
0
12
45
0
0
23
0
0
0
0
0
45
0
0
% Q
% Arg:
45
0
0
0
0
0
0
34
12
0
0
0
12
0
0
% R
% Ser:
0
23
0
0
34
0
0
45
23
0
0
23
0
0
12
% S
% Thr:
0
12
23
0
0
12
0
0
0
0
0
0
0
23
12
% T
% Val:
12
0
0
0
0
0
0
12
0
45
12
0
0
0
0
% V
% Trp:
0
0
0
0
0
23
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _