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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NDUFS4 All Species: 14.24
Human Site: T47 Identified Species: 28.48
UniProt: O43181 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.27
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43181 NP_002486.1 175 20108 T47 W R L A Q D Q T Q D T Q L I T
Chimpanzee Pan troglodytes Q0MQH1 175 20042 T47 W R L A Q D Q T Q D T Q L I T
Rhesus Macaque Macaca mulatta XP_001096347 174 19889 Q47 R L A Q D Q T Q D T Q L I T V
Dog Lupus familis XP_536474 175 19752 A47 W R L A Q D Q A R D T Q L I T
Cat Felis silvestris
Mouse Mus musculus Q9CXZ1 175 19766 T47 W K L A D N Q T R D T Q L I T
Rat Rattus norvegicus Q5XIF3 175 19722 T47 W K L A D G Q T R D T Q L I T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507034 372 42044 A244 W L L A E D Q A R D T Q L I T
Chicken Gallus gallus
Frog Xenopus laevis NP_001087349 166 18978 K39 R L A Q T Q A K D T Q L I T V
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_573385 183 20663 N54 P E E L E Q R N K L S G K I T
Honey Bee Apis mellifera XP_001123307 167 19353 R40 E K L A R E A R K E A V I I V
Nematode Worm Caenorhab. elegans NP_491359 176 19975 S48 N D I L D K P S Q K T P V K V
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P25711 218 24455 K88 S T W T P V P K H I Q N G S E
Conservation
Percent
Protein Identity: 100 99.4 96 91.4 N.A. 87.4 88 N.A. 40.8 N.A. 76 N.A. N.A. 43.7 45.7 44.3 N.A.
Protein Similarity: 100 99.4 96.5 94.2 N.A. 94.2 93.1 N.A. 44.3 N.A. 86.2 N.A. N.A. 61.7 64 57.3 N.A.
P-Site Identity: 100 100 0 86.6 N.A. 73.3 73.3 N.A. 73.3 N.A. 0 N.A. N.A. 13.3 20 13.3 N.A.
P-Site Similarity: 100 100 6.6 93.3 N.A. 93.3 86.6 N.A. 86.6 N.A. 6.6 N.A. N.A. 40 60 33.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 30.2
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 48.6
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 0
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 0
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 17 59 0 0 17 17 0 0 9 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 9 0 0 34 34 0 0 17 50 0 0 0 0 0 % D
% Glu: 9 9 9 0 17 9 0 0 0 9 0 0 0 0 9 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 9 0 0 0 0 0 9 9 0 0 % G
% His: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % H
% Ile: 0 0 9 0 0 0 0 0 0 9 0 0 25 67 0 % I
% Lys: 0 25 0 0 0 9 0 17 17 9 0 0 9 9 0 % K
% Leu: 0 25 59 17 0 0 0 0 0 9 0 17 50 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 9 0 0 0 0 9 0 9 0 0 0 9 0 0 0 % N
% Pro: 9 0 0 0 9 0 17 0 0 0 0 9 0 0 0 % P
% Gln: 0 0 0 17 25 25 50 9 25 0 25 50 0 0 0 % Q
% Arg: 17 25 0 0 9 0 9 9 34 0 0 0 0 0 0 % R
% Ser: 9 0 0 0 0 0 0 9 0 0 9 0 0 9 0 % S
% Thr: 0 9 0 9 9 0 9 34 0 17 59 0 0 17 59 % T
% Val: 0 0 0 0 0 9 0 0 0 0 0 9 9 0 34 % V
% Trp: 50 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _