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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ARHGAP6
All Species:
23.33
Human Site:
S667
Identified Species:
64.17
UniProt:
O43182
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43182
NP_006116.2
974
105947
S667
K
A
S
S
G
D
I
S
P
Y
D
N
N
S
P
Chimpanzee
Pan troglodytes
XP_001143524
974
105855
S667
K
A
S
S
G
D
I
S
P
Y
D
N
N
S
P
Rhesus Macaque
Macaca mulatta
XP_001094565
977
106269
S667
K
A
S
S
G
D
I
S
P
Y
D
N
N
S
P
Dog
Lupus familis
XP_548858
980
107378
S664
K
A
S
S
G
D
L
S
P
Y
D
N
N
S
P
Cat
Felis silvestris
Mouse
Mus musculus
O54834
987
108825
S669
K
A
S
S
G
D
I
S
P
Y
D
N
N
S
P
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515086
802
89053
E511
E
K
L
Y
K
V
P
E
Q
Y
M
L
V
G
H
Chicken
Gallus gallus
XP_416840
969
107211
S651
K
A
S
S
G
D
V
S
P
Y
D
N
N
S
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001038371
630
71247
S339
T
V
Q
E
N
A
N
S
S
T
G
P
N
K
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787163
867
97006
N576
G
S
A
G
A
R
T
N
A
R
R
N
N
M
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
97
87.3
N.A.
85.1
N.A.
N.A.
67.9
63
N.A.
31.6
N.A.
N.A.
N.A.
N.A.
27.9
Protein Similarity:
100
99.5
97.7
90.6
N.A.
88.6
N.A.
N.A.
72
71.3
N.A.
43.8
N.A.
N.A.
N.A.
N.A.
42.9
P-Site Identity:
100
100
100
93.3
N.A.
100
N.A.
N.A.
6.6
93.3
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
13.3
100
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
67
12
0
12
12
0
0
12
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
67
0
0
0
0
67
0
0
0
0
% D
% Glu:
12
0
0
12
0
0
0
12
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
12
0
0
12
67
0
0
0
0
0
12
0
0
12
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% H
% Ile:
0
0
0
0
0
0
45
0
0
0
0
0
0
0
0
% I
% Lys:
67
12
0
0
12
0
0
0
0
0
0
0
0
12
0
% K
% Leu:
0
0
12
0
0
0
12
0
0
0
0
12
0
0
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
12
0
0
12
0
% M
% Asn:
0
0
0
0
12
0
12
12
0
0
0
78
89
0
0
% N
% Pro:
0
0
0
0
0
0
12
0
67
0
0
12
0
0
67
% P
% Gln:
0
0
12
0
0
0
0
0
12
0
0
0
0
0
12
% Q
% Arg:
0
0
0
0
0
12
0
0
0
12
12
0
0
0
0
% R
% Ser:
0
12
67
67
0
0
0
78
12
0
0
0
0
67
0
% S
% Thr:
12
0
0
0
0
0
12
0
0
12
0
0
0
0
0
% T
% Val:
0
12
0
0
0
12
12
0
0
0
0
0
12
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
12
0
0
0
0
0
78
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _