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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ARHGAP6
All Species:
14.24
Human Site:
T246
Identified Species:
39.17
UniProt:
O43182
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43182
NP_006116.2
974
105947
T246
C
D
L
S
C
Q
I
T
I
P
K
D
G
Q
K
Chimpanzee
Pan troglodytes
XP_001143524
974
105855
T246
C
D
L
S
C
Q
I
T
I
P
K
D
G
Q
K
Rhesus Macaque
Macaca mulatta
XP_001094565
977
106269
T246
C
D
L
S
C
Q
I
T
I
P
K
D
G
Q
K
Dog
Lupus familis
XP_548858
980
107378
K246
S
C
P
I
T
I
P
K
D
G
Q
K
R
K
K
Cat
Felis silvestris
Mouse
Mus musculus
O54834
987
108825
T247
C
D
L
G
C
Q
I
T
I
P
K
D
G
Q
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515086
802
89053
L107
A
N
D
R
A
Y
K
L
K
Q
D
S
Q
K
E
Chicken
Gallus gallus
XP_416840
969
107211
L246
K
K
S
L
R
K
K
L
D
S
L
G
K
E
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001038371
630
71247
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787163
867
97006
S172
K
Q
R
E
R
R
E
S
L
D
L
A
Q
P
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
97
87.3
N.A.
85.1
N.A.
N.A.
67.9
63
N.A.
31.6
N.A.
N.A.
N.A.
N.A.
27.9
Protein Similarity:
100
99.5
97.7
90.6
N.A.
88.6
N.A.
N.A.
72
71.3
N.A.
43.8
N.A.
N.A.
N.A.
N.A.
42.9
P-Site Identity:
100
100
100
6.6
N.A.
93.3
N.A.
N.A.
0
6.6
N.A.
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
20
N.A.
93.3
N.A.
N.A.
20
20
N.A.
0
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
0
12
0
0
0
0
0
0
12
0
0
0
% A
% Cys:
45
12
0
0
45
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
45
12
0
0
0
0
0
23
12
12
45
0
0
0
% D
% Glu:
0
0
0
12
0
0
12
0
0
0
0
0
0
12
12
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
12
0
0
0
0
0
12
0
12
45
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
12
0
12
45
0
45
0
0
0
0
0
0
% I
% Lys:
23
12
0
0
0
12
23
12
12
0
45
12
12
23
67
% K
% Leu:
0
0
45
12
0
0
0
23
12
0
23
0
0
0
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
12
0
0
0
12
0
0
45
0
0
0
12
0
% P
% Gln:
0
12
0
0
0
45
0
0
0
12
12
0
23
45
0
% Q
% Arg:
0
0
12
12
23
12
0
0
0
0
0
0
12
0
0
% R
% Ser:
12
0
12
34
0
0
0
12
0
12
0
12
0
0
0
% S
% Thr:
0
0
0
0
12
0
0
45
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _