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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADAM12
All Species:
11.21
Human Site:
T867
Identified Species:
24.67
UniProt:
O43184
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43184
NP_003465.3
909
99542
T867
A
D
P
L
A
R
T
T
R
L
T
H
A
L
A
Chimpanzee
Pan troglodytes
XP_508106
914
100282
T872
A
D
P
L
A
R
T
T
R
L
T
H
A
L
A
Rhesus Macaque
Macaca mulatta
XP_001087980
909
99411
T867
A
D
P
L
A
R
T
T
R
L
T
H
A
L
A
Dog
Lupus familis
XP_546274
909
99674
K862
A
N
P
V
P
G
R
K
S
L
P
R
P
G
G
Cat
Felis silvestris
Mouse
Mus musculus
Q61824
903
98582
R861
L
P
A
D
P
L
S
R
T
S
R
L
T
S
A
Rat
Rattus norvegicus
Q9QYV0
816
88034
L775
P
P
P
P
R
K
P
L
P
A
N
P
Q
G
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507222
856
93750
K808
A
S
P
V
P
G
R
K
V
V
P
G
S
V
P
Chicken
Gallus gallus
NP_001136322
922
101009
T879
P
A
D
P
L
N
K
T
R
Y
N
S
A
C
T
Frog
Xenopus laevis
O42596
935
104143
S891
S
N
S
T
E
T
L
S
P
A
K
S
P
S
S
Zebra Danio
Brachydanio rerio
XP_001921148
773
83366
L732
R
N
P
S
N
I
R
L
P
A
P
V
P
K
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_999635
1023
111059
N968
S
S
N
F
S
P
T
N
K
V
S
E
P
F
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.3
94.8
43.7
N.A.
80.3
35.5
N.A.
43.3
71.5
28.3
56.7
N.A.
N.A.
N.A.
N.A.
35.8
Protein Similarity:
100
95.9
97.1
59.4
N.A.
88.1
50.3
N.A.
58
82.4
44.4
65.2
N.A.
N.A.
N.A.
N.A.
51.2
P-Site Identity:
100
100
100
20
N.A.
6.6
6.6
N.A.
13.3
20
0
6.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
33.3
N.A.
13.3
13.3
N.A.
40
20
26.6
13.3
N.A.
N.A.
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
46
10
10
0
28
0
0
0
0
28
0
0
37
0
46
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% C
% Asp:
0
28
10
10
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
10
0
0
0
0
0
0
10
0
0
0
% E
% Phe:
0
0
0
10
0
0
0
0
0
0
0
0
0
10
0
% F
% Gly:
0
0
0
0
0
19
0
0
0
0
0
10
0
19
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
28
0
0
0
% H
% Ile:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
10
10
19
10
0
10
0
0
10
0
% K
% Leu:
10
0
0
28
10
10
10
19
0
37
0
10
0
28
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
28
10
0
10
10
0
10
0
0
19
0
0
0
0
% N
% Pro:
19
19
64
19
28
10
10
0
28
0
28
10
37
0
19
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% Q
% Arg:
10
0
0
0
10
28
28
10
37
0
10
10
0
0
10
% R
% Ser:
19
19
10
10
10
0
10
10
10
10
10
19
10
19
10
% S
% Thr:
0
0
0
10
0
10
37
37
10
0
28
0
10
0
10
% T
% Val:
0
0
0
19
0
0
0
0
10
19
0
10
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _