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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CRX
All Species:
10
Human Site:
S150
Identified Species:
22
UniProt:
O43186
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43186
NP_000545.1
299
32261
S150
S
P
P
L
P
G
P
S
G
S
P
T
T
A
V
Chimpanzee
Pan troglodytes
XP_524319
298
32142
S149
S
P
P
L
P
G
P
S
G
S
P
T
T
A
V
Rhesus Macaque
Macaca mulatta
NP_001171116
297
32414
P148
P
P
D
S
T
S
V
P
T
I
A
S
S
S
A
Dog
Lupus familis
XP_547830
289
31604
P140
P
P
S
S
T
S
V
P
A
I
S
S
S
S
A
Cat
Felis silvestris
Mouse
Mus musculus
O54751
299
32356
S150
S
P
S
L
P
G
P
S
G
S
P
T
T
A
V
Rat
Rattus norvegicus
Q63410
355
37584
A164
L
G
G
N
P
V
A
A
A
S
S
L
S
T
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q9PVM0
290
31534
S141
P
G
T
A
V
T
P
S
S
T
A
G
A
T
V
Zebra Danio
Brachydanio rerio
Q91981
289
31576
V139
T
P
P
S
S
T
S
V
P
A
I
S
T
T
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P22810
542
55168
N179
T
Q
S
S
G
G
N
N
S
N
K
S
S
Q
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q93356
278
30883
L130
D
V
L
D
G
E
P
L
K
G
G
S
P
G
Y
Sea Urchin
Strong. purpuratus
Q26417
371
41197
D222
P
P
T
P
R
E
N
D
A
P
T
T
T
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
55.1
54.8
N.A.
96.6
40.2
N.A.
N.A.
N.A.
58.1
54.1
N.A.
26.3
N.A.
31.4
34.5
Protein Similarity:
100
99.3
67.2
67.5
N.A.
97.3
54.3
N.A.
N.A.
N.A.
72.5
66.5
N.A.
34.8
N.A.
46.4
46.9
P-Site Identity:
100
100
6.6
6.6
N.A.
93.3
13.3
N.A.
N.A.
N.A.
20
20
N.A.
6.6
N.A.
6.6
20
P-Site Similarity:
100
100
26.6
26.6
N.A.
93.3
26.6
N.A.
N.A.
N.A.
26.6
40
N.A.
40
N.A.
13.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
10
10
28
10
19
0
10
28
19
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
10
10
0
0
0
10
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
19
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
19
10
0
19
37
0
0
28
10
10
10
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
19
10
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
10
0
10
0
0
0
10
% K
% Leu:
10
0
10
28
0
0
0
10
0
0
0
10
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
19
10
0
10
0
0
0
0
0
% N
% Pro:
37
64
28
10
37
0
46
19
10
10
28
0
10
0
10
% P
% Gln:
0
10
0
0
0
0
0
0
0
0
0
0
0
10
0
% Q
% Arg:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
28
0
28
37
10
19
10
37
19
37
19
46
37
28
10
% S
% Thr:
19
0
19
0
19
19
0
0
10
10
10
37
46
28
10
% T
% Val:
0
10
0
0
10
10
19
10
0
0
0
0
0
0
37
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _