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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CRX
All Species:
12.42
Human Site:
S249
Identified Species:
27.33
UniProt:
O43186
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43186
NP_000545.1
299
32261
S249
V
G
P
S
L
A
Q
S
P
T
S
L
S
G
Q
Chimpanzee
Pan troglodytes
XP_524319
298
32142
S248
V
G
P
S
L
A
Q
S
P
T
S
L
S
G
Q
Rhesus Macaque
Macaca mulatta
NP_001171116
297
32414
S247
N
Q
S
P
A
S
L
S
T
Q
G
Y
G
A
S
Dog
Lupus familis
XP_547830
289
31604
S239
N
Q
S
P
A
S
L
S
T
Q
G
Y
G
A
S
Cat
Felis silvestris
Mouse
Mus musculus
O54751
299
32356
S249
V
G
P
S
L
A
Q
S
P
T
S
L
S
G
Q
Rat
Rattus norvegicus
Q63410
355
37584
Q263
H
S
H
H
H
P
H
Q
L
S
P
M
A
P
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q9PVM0
290
31534
L240
L
S
Q
S
P
A
S
L
S
A
Q
G
Y
G
A
Zebra Danio
Brachydanio rerio
Q91981
289
31576
L238
L
N
Q
S
P
A
S
L
P
T
Q
G
Y
G
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P22810
542
55168
G278
G
G
G
S
Q
A
G
G
H
L
S
A
A
A
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q93356
278
30883
T229
A
T
S
S
L
P
T
T
S
S
S
L
S
V
Y
Sea Urchin
Strong. purpuratus
Q26417
371
41197
Q321
F
P
G
S
I
N
H
Q
M
A
A
S
A
M
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
55.1
54.8
N.A.
96.6
40.2
N.A.
N.A.
N.A.
58.1
54.1
N.A.
26.3
N.A.
31.4
34.5
Protein Similarity:
100
99.3
67.2
67.5
N.A.
97.3
54.3
N.A.
N.A.
N.A.
72.5
66.5
N.A.
34.8
N.A.
46.4
46.9
P-Site Identity:
100
100
6.6
6.6
N.A.
100
0
N.A.
N.A.
N.A.
20
33.3
N.A.
26.6
N.A.
33.3
6.6
P-Site Similarity:
100
100
13.3
13.3
N.A.
100
20
N.A.
N.A.
N.A.
26.6
40
N.A.
33.3
N.A.
46.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
19
55
0
0
0
19
10
10
28
28
28
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
37
19
0
0
0
10
10
0
0
19
19
19
46
0
% G
% His:
10
0
10
10
10
0
19
0
10
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
19
0
0
0
37
0
19
19
10
10
0
37
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
10
0
10
0
% M
% Asn:
19
10
0
0
0
10
0
0
0
0
0
0
0
0
10
% N
% Pro:
0
10
28
19
19
19
0
0
37
0
10
0
0
10
0
% P
% Gln:
0
19
19
0
10
0
28
19
0
19
19
0
0
0
28
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
19
28
73
0
19
19
46
19
19
46
10
37
0
28
% S
% Thr:
0
10
0
0
0
0
10
10
19
37
0
0
0
0
0
% T
% Val:
28
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
19
19
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _