KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CRX
All Species:
14.85
Human Site:
T251
Identified Species:
32.67
UniProt:
O43186
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43186
NP_000545.1
299
32261
T251
P
S
L
A
Q
S
P
T
S
L
S
G
Q
S
Y
Chimpanzee
Pan troglodytes
XP_524319
298
32142
T250
P
S
L
A
Q
S
P
T
S
L
S
G
Q
S
Y
Rhesus Macaque
Macaca mulatta
NP_001171116
297
32414
Q249
S
P
A
S
L
S
T
Q
G
Y
G
A
S
S
L
Dog
Lupus familis
XP_547830
289
31604
Q241
S
P
A
S
L
S
T
Q
G
Y
G
A
S
S
L
Cat
Felis silvestris
Mouse
Mus musculus
O54751
299
32356
T251
P
S
L
A
Q
S
P
T
S
L
S
G
Q
S
Y
Rat
Rattus norvegicus
Q63410
355
37584
S265
H
H
H
P
H
Q
L
S
P
M
A
P
S
S
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q9PVM0
290
31534
A242
Q
S
P
A
S
L
S
A
Q
G
Y
G
A
S
S
Zebra Danio
Brachydanio rerio
Q91981
289
31576
T240
Q
S
P
A
S
L
P
T
Q
G
Y
G
A
S
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P22810
542
55168
L280
G
S
Q
A
G
G
H
L
S
A
A
A
A
A
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q93356
278
30883
S231
S
S
L
P
T
T
S
S
S
L
S
V
Y
N
Y
Sea Urchin
Strong. purpuratus
Q26417
371
41197
A323
G
S
I
N
H
Q
M
A
A
S
A
M
N
N
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
55.1
54.8
N.A.
96.6
40.2
N.A.
N.A.
N.A.
58.1
54.1
N.A.
26.3
N.A.
31.4
34.5
Protein Similarity:
100
99.3
67.2
67.5
N.A.
97.3
54.3
N.A.
N.A.
N.A.
72.5
66.5
N.A.
34.8
N.A.
46.4
46.9
P-Site Identity:
100
100
13.3
13.3
N.A.
100
6.6
N.A.
N.A.
N.A.
26.6
40
N.A.
20
N.A.
40
6.6
P-Site Similarity:
100
100
20
20
N.A.
100
26.6
N.A.
N.A.
N.A.
26.6
40
N.A.
33.3
N.A.
60
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
19
55
0
0
0
19
10
10
28
28
28
10
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
19
0
0
0
10
10
0
0
19
19
19
46
0
0
19
% G
% His:
10
10
10
0
19
0
10
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
37
0
19
19
10
10
0
37
0
0
0
0
19
% L
% Met:
0
0
0
0
0
0
10
0
0
10
0
10
0
0
10
% M
% Asn:
0
0
0
10
0
0
0
0
0
0
0
0
10
19
0
% N
% Pro:
28
19
19
19
0
0
37
0
10
0
0
10
0
0
0
% P
% Gln:
19
0
10
0
28
19
0
19
19
0
0
0
28
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
28
73
0
19
19
46
19
19
46
10
37
0
28
73
10
% S
% Thr:
0
0
0
0
10
10
19
37
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
19
19
0
10
0
37
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _