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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CRX
All Species:
9.7
Human Site:
Y142
Identified Species:
21.33
UniProt:
O43186
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43186
NP_000545.1
299
32261
Y142
P
L
G
I
S
D
S
Y
S
P
P
L
P
G
P
Chimpanzee
Pan troglodytes
XP_524319
298
32142
Y141
P
L
G
I
S
D
S
Y
S
P
P
L
P
G
P
Rhesus Macaque
Macaca mulatta
NP_001171116
297
32414
T140
S
G
T
S
G
Q
F
T
P
P
D
S
T
S
V
Dog
Lupus familis
XP_547830
289
31604
T132
S
G
T
S
G
Q
F
T
P
P
S
S
T
S
V
Cat
Felis silvestris
Mouse
Mus musculus
O54751
299
32356
Y142
P
L
G
I
S
D
S
Y
S
P
S
L
P
G
P
Rat
Rattus norvegicus
Q63410
355
37584
G156
P
A
A
A
A
A
A
G
L
G
G
N
P
V
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q9PVM0
290
31534
P133
N
G
Q
Y
S
P
P
P
P
G
T
A
V
T
P
Zebra Danio
Brachydanio rerio
Q91981
289
31576
F131
E
S
G
A
S
G
Q
F
T
P
P
S
S
T
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P22810
542
55168
N171
N
G
S
S
S
N
N
N
T
Q
S
S
G
G
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q93356
278
30883
T122
K
S
E
D
Q
Q
Q
T
D
V
L
D
G
E
P
Sea Urchin
Strong. purpuratus
Q26417
371
41197
P214
R
P
A
K
K
K
T
P
P
P
T
P
R
E
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
55.1
54.8
N.A.
96.6
40.2
N.A.
N.A.
N.A.
58.1
54.1
N.A.
26.3
N.A.
31.4
34.5
Protein Similarity:
100
99.3
67.2
67.5
N.A.
97.3
54.3
N.A.
N.A.
N.A.
72.5
66.5
N.A.
34.8
N.A.
46.4
46.9
P-Site Identity:
100
100
6.6
6.6
N.A.
93.3
13.3
N.A.
N.A.
N.A.
13.3
26.6
N.A.
13.3
N.A.
6.6
6.6
P-Site Similarity:
100
100
6.6
6.6
N.A.
93.3
26.6
N.A.
N.A.
N.A.
13.3
40
N.A.
33.3
N.A.
6.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
19
19
10
10
10
0
0
0
0
10
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
28
0
0
10
0
10
10
0
0
0
% D
% Glu:
10
0
10
0
0
0
0
0
0
0
0
0
0
19
0
% E
% Phe:
0
0
0
0
0
0
19
10
0
0
0
0
0
0
0
% F
% Gly:
0
37
37
0
19
10
0
10
0
19
10
0
19
37
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
28
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
0
0
10
10
10
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
28
0
0
0
0
0
0
10
0
10
28
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
19
0
0
0
0
10
10
10
0
0
0
10
0
0
19
% N
% Pro:
37
10
0
0
0
10
10
19
37
64
28
10
37
0
46
% P
% Gln:
0
0
10
0
10
28
19
0
0
10
0
0
0
0
0
% Q
% Arg:
10
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% R
% Ser:
19
19
10
28
55
0
28
0
28
0
28
37
10
19
10
% S
% Thr:
0
0
19
0
0
0
10
28
19
0
19
0
19
19
0
% T
% Val:
0
0
0
0
0
0
0
0
0
10
0
0
10
10
19
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
28
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _