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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MLNR All Species: 8.79
Human Site: S211 Identified Species: 17.58
UniProt: O43193 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43193 NP_001498.1 412 45344 S211 S S P P L W L S R A P P P S P
Chimpanzee Pan troglodytes XP_001149683 324 34804 Q134 L P F L F R F Q P P P A G T S
Rhesus Macaque Macaca mulatta XP_001101857 412 45230 S211 S S P P L W L S R A P P P S P
Dog Lupus familis XP_543088 421 46451 R215 F T M G Q Q N R S A D G H H P
Cat Felis silvestris
Mouse Mus musculus Q99P50 364 40951 A174 W A V A F C S A G P I F V L V
Rat Rattus norvegicus O08725 364 40945 A174 W A V A F C S A G P I F V L V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513979 469 50826 S277 S S S S S S P S A A P A S A L
Chicken Gallus gallus O93603 395 44679 Y202 M M D F G I F Y V L P M V L A
Frog Xenopus laevis P35373 363 41522 I173 V I Y R Q I F I F P D T N Q T
Zebra Danio Brachydanio rerio A0T2N3 359 40129 T169 S G V L A A P T L L F R T T V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8ITC7 477 53986 S244 E I P V F E V S F C I F F V I
Honey Bee Apis mellifera NP_001091702 381 43850 S191 L V E Y P P E S G N Y S A D S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 52.1 93.6 33.9 N.A. 45.8 46.1 N.A. 60.5 23.2 24.7 21.6 N.A. 23.4 29.3 N.A. N.A.
Protein Similarity: 100 57 95.8 51 N.A. 60.4 60.4 N.A. 68.2 45.6 43.2 41.7 N.A. 37.9 48 N.A. N.A.
P-Site Identity: 100 6.6 100 13.3 N.A. 0 0 N.A. 33.3 6.6 0 6.6 N.A. 13.3 6.6 N.A. N.A.
P-Site Similarity: 100 13.3 100 20 N.A. 13.3 13.3 N.A. 40 6.6 0 20 N.A. 20 6.6 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 17 0 17 9 9 0 17 9 34 0 17 9 9 9 % A
% Cys: 0 0 0 0 0 17 0 0 0 9 0 0 0 0 0 % C
% Asp: 0 0 9 0 0 0 0 0 0 0 17 0 0 9 0 % D
% Glu: 9 0 9 0 0 9 9 0 0 0 0 0 0 0 0 % E
% Phe: 9 0 9 9 34 0 25 0 17 0 9 25 9 0 0 % F
% Gly: 0 9 0 9 9 0 0 0 25 0 0 9 9 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 9 9 0 % H
% Ile: 0 17 0 0 0 17 0 9 0 0 25 0 0 0 9 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 17 0 0 17 17 0 17 0 9 17 0 0 0 25 9 % L
% Met: 9 9 9 0 0 0 0 0 0 0 0 9 0 0 0 % M
% Asn: 0 0 0 0 0 0 9 0 0 9 0 0 9 0 0 % N
% Pro: 0 9 25 17 9 9 17 0 9 34 42 17 17 0 25 % P
% Gln: 0 0 0 0 17 9 0 9 0 0 0 0 0 9 0 % Q
% Arg: 0 0 0 9 0 9 0 9 17 0 0 9 0 0 0 % R
% Ser: 34 25 9 9 9 9 17 42 9 0 0 9 9 17 17 % S
% Thr: 0 9 0 0 0 0 0 9 0 0 0 9 9 17 9 % T
% Val: 9 9 25 9 0 0 9 0 9 0 0 0 25 9 25 % V
% Trp: 17 0 0 0 0 17 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 9 9 0 0 0 9 0 0 9 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _