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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MLNR
All Species:
5.76
Human Site:
S277
Identified Species:
11.52
UniProt:
O43193
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43193
NP_001498.1
412
45344
S277
I
G
R
E
L
W
S
S
R
R
P
L
R
G
P
Chimpanzee
Pan troglodytes
XP_001149683
324
34804
N200
W
G
V
Y
L
L
P
N
A
F
V
N
P
G
A
Rhesus Macaque
Macaca mulatta
XP_001101857
412
45230
S277
I
G
R
E
L
W
S
S
R
R
P
L
R
G
P
Dog
Lupus familis
XP_543088
421
46451
T281
A
E
Q
G
Q
V
C
T
V
G
D
Q
H
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q99P50
364
40951
R240
L
I
G
R
K
L
W
R
R
R
G
D
A
A
V
Rat
Rattus norvegicus
O08725
364
40945
R240
L
I
G
R
K
L
W
R
R
R
G
D
A
A
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513979
469
50826
L343
H
R
R
T
V
R
L
L
V
V
V
V
L
A
F
Chicken
Gallus gallus
O93603
395
44679
K268
A
S
R
R
Q
V
T
K
M
L
A
V
V
V
V
Frog
Xenopus laevis
P35373
363
41522
F239
R
A
R
N
D
D
I
F
K
M
I
V
A
V
V
Zebra Danio
Brachydanio rerio
A0T2N3
359
40129
T235
G
F
I
G
C
T
V
T
R
H
F
N
S
L
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8ITC7
477
53986
C310
V
V
I
T
F
F
V
C
W
F
P
F
H
L
Q
Honey Bee
Apis mellifera
NP_001091702
381
43850
G257
V
V
Q
G
A
I
H
G
D
S
R
Q
I
Q
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
52.1
93.6
33.9
N.A.
45.8
46.1
N.A.
60.5
23.2
24.7
21.6
N.A.
23.4
29.3
N.A.
N.A.
Protein Similarity:
100
57
95.8
51
N.A.
60.4
60.4
N.A.
68.2
45.6
43.2
41.7
N.A.
37.9
48
N.A.
N.A.
P-Site Identity:
100
20
100
0
N.A.
13.3
13.3
N.A.
6.6
6.6
6.6
6.6
N.A.
6.6
0
N.A.
N.A.
P-Site Similarity:
100
26.6
100
13.3
N.A.
20
20
N.A.
20
20
20
13.3
N.A.
20
13.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
9
0
0
9
0
0
0
9
0
9
0
25
25
9
% A
% Cys:
0
0
0
0
9
0
9
9
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
9
9
0
0
9
0
9
17
0
0
0
% D
% Glu:
0
9
0
17
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
9
0
0
9
9
0
9
0
17
9
9
0
0
9
% F
% Gly:
9
25
17
25
0
0
0
9
0
9
17
0
0
25
0
% G
% His:
9
0
0
0
0
0
9
0
0
9
0
0
17
0
0
% H
% Ile:
17
17
17
0
0
9
9
0
0
0
9
0
9
0
0
% I
% Lys:
0
0
0
0
17
0
0
9
9
0
0
0
0
0
0
% K
% Leu:
17
0
0
0
25
25
9
9
0
9
0
17
9
17
0
% L
% Met:
0
0
0
0
0
0
0
0
9
9
0
0
0
0
0
% M
% Asn:
0
0
0
9
0
0
0
9
0
0
0
17
0
0
0
% N
% Pro:
0
0
0
0
0
0
9
0
0
0
25
0
9
0
17
% P
% Gln:
0
0
17
0
17
0
0
0
0
0
0
17
0
9
9
% Q
% Arg:
9
9
42
25
0
9
0
17
42
34
9
0
17
0
9
% R
% Ser:
0
9
0
0
0
0
17
17
0
9
0
0
9
9
17
% S
% Thr:
0
0
0
17
0
9
9
17
0
0
0
0
0
0
0
% T
% Val:
17
17
9
0
9
17
17
0
17
9
17
25
9
17
34
% V
% Trp:
9
0
0
0
0
17
17
0
9
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _