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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GPR39
All Species:
10
Human Site:
S185
Identified Species:
15.71
UniProt:
O43194
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43194
NP_001499.1
453
51329
S185
Y
P
L
V
N
V
P
S
H
R
G
L
T
C
N
Chimpanzee
Pan troglodytes
XP_515800
453
51339
S185
Y
P
L
V
N
V
P
S
H
R
G
L
T
C
N
Rhesus Macaque
Macaca mulatta
O97666
380
42588
R127
L
T
G
L
S
F
D
R
Y
L
A
I
V
R
P
Dog
Lupus familis
XP_853332
465
51886
N185
Y
P
L
V
H
V
P
N
H
A
G
L
S
C
N
Cat
Felis silvestris
Mouse
Mus musculus
Q5U431
456
51571
T185
Y
P
L
V
N
V
P
T
H
K
G
L
N
C
N
Rat
Rattus norvegicus
P20789
424
47036
A170
L
S
V
E
R
Y
L
A
I
C
H
P
F
K
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506365
416
46666
E163
N
I
A
S
L
S
L
E
R
Y
M
A
I
C
H
Chicken
Gallus gallus
O93603
395
44679
F141
K
A
Q
F
L
C
T
F
S
R
A
K
K
I
I
Frog
Xenopus laevis
O42574
385
43291
D132
T
L
C
V
I
S
I
D
R
Y
I
A
I
T
S
Zebra Danio
Brachydanio rerio
NP_956711
440
49140
L186
N
L
T
F
C
T
S
L
S
Q
H
W
V
M
Y
Tiger Blowfish
Takifugu rubipres
NP_001098705
417
46824
I164
L
V
A
L
P
L
L
I
A
T
G
T
Q
G
H
Fruit Fly
Dros. melanogaster
Q8ITC7
477
53986
S200
L
W
I
V
S
F
I
S
A
I
P
F
G
L
L
Honey Bee
Apis mellifera
NP_001091688
581
66278
V204
Y
E
N
K
N
G
S
V
I
L
D
T
A
R
C
Nematode Worm
Caenorhab. elegans
NP_493666
403
46055
A150
I
F
S
T
L
W
R
A
N
V
L
I
I
L
A
Sea Urchin
Strong. purpuratus
XP_797514
357
41080
A104
T
T
V
L
H
I
T
A
F
T
I
E
R
Y
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
21.8
69.8
N.A.
81.1
27.5
N.A.
27.1
21.4
20
45.2
46.5
23
21.3
25.1
22.9
Protein Similarity:
100
99.5
40.6
79.7
N.A.
87.2
44.8
N.A.
45.2
40.4
40.6
61.5
64.2
44.8
39.5
45.9
41.9
P-Site Identity:
100
100
0
73.3
N.A.
80
0
N.A.
6.6
6.6
6.6
0
6.6
13.3
13.3
0
0
P-Site Similarity:
100
100
26.6
93.3
N.A.
93.3
13.3
N.A.
13.3
6.6
13.3
6.6
26.6
26.6
13.3
20
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
14
0
0
0
0
20
14
7
14
14
7
0
14
% A
% Cys:
0
0
7
0
7
7
0
0
0
7
0
0
0
34
7
% C
% Asp:
0
0
0
0
0
0
7
7
0
0
7
0
0
0
0
% D
% Glu:
0
7
0
7
0
0
0
7
0
0
0
7
0
0
0
% E
% Phe:
0
7
0
14
0
14
0
7
7
0
0
7
7
0
0
% F
% Gly:
0
0
7
0
0
7
0
0
0
0
34
0
7
7
0
% G
% His:
0
0
0
0
14
0
0
0
27
0
14
0
0
0
14
% H
% Ile:
7
7
7
0
7
7
14
7
14
7
14
14
20
7
7
% I
% Lys:
7
0
0
7
0
0
0
0
0
7
0
7
7
7
0
% K
% Leu:
27
14
27
20
20
7
20
7
0
14
7
27
0
14
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
7
0
0
7
0
% M
% Asn:
14
0
7
0
27
0
0
7
7
0
0
0
7
0
27
% N
% Pro:
0
27
0
0
7
0
27
0
0
0
7
7
0
0
7
% P
% Gln:
0
0
7
0
0
0
0
0
0
7
0
0
7
0
0
% Q
% Arg:
0
0
0
0
7
0
7
7
14
20
0
0
7
14
0
% R
% Ser:
0
7
7
7
14
14
14
20
14
0
0
0
7
0
7
% S
% Thr:
14
14
7
7
0
7
14
7
0
14
0
14
14
7
0
% T
% Val:
0
7
14
40
0
27
0
7
0
7
0
0
14
0
7
% V
% Trp:
0
7
0
0
0
7
0
0
0
0
0
7
0
0
0
% W
% Tyr:
34
0
0
0
0
7
0
0
7
14
0
0
0
7
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _