KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GPR39
All Species:
14.85
Human Site:
S194
Identified Species:
23.33
UniProt:
O43194
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43194
NP_001499.1
453
51329
S194
R
G
L
T
C
N
R
S
S
T
R
H
H
E
Q
Chimpanzee
Pan troglodytes
XP_515800
453
51339
S194
R
G
L
T
C
N
R
S
S
T
R
H
H
E
Q
Rhesus Macaque
Macaca mulatta
O97666
380
42588
A136
L
A
I
V
R
P
V
A
N
A
R
L
R
L
R
Dog
Lupus familis
XP_853332
465
51886
T194
A
G
L
S
C
N
R
T
R
T
R
H
H
E
R
Cat
Felis silvestris
Mouse
Mus musculus
Q5U431
456
51571
S194
K
G
L
N
C
N
L
S
R
T
R
H
H
D
E
Rat
Rattus norvegicus
P20789
424
47036
T179
C
H
P
F
K
A
K
T
L
M
S
R
S
R
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506365
416
46666
F172
Y
M
A
I
C
H
P
F
K
A
K
S
V
M
S
Chicken
Gallus gallus
O93603
395
44679
F150
R
A
K
K
I
I
I
F
V
W
S
F
A
S
V
Frog
Xenopus laevis
O42574
385
43291
F141
Y
I
A
I
T
S
P
F
R
Y
Q
S
L
L
T
Zebra Danio
Brachydanio rerio
NP_956711
440
49140
T195
Q
H
W
V
M
Y
R
T
S
I
F
T
A
F
V
Tiger Blowfish
Takifugu rubipres
NP_001098705
417
46824
P173
T
G
T
Q
G
H
I
P
L
R
A
D
T
P
V
Fruit Fly
Dros. melanogaster
Q8ITC7
477
53986
D209
I
P
F
G
L
L
S
D
I
Q
Y
L
N
Y
P
Honey Bee
Apis mellifera
NP_001091688
581
66278
M213
L
D
T
A
R
C
S
M
K
W
T
L
I
E
H
Nematode Worm
Caenorhab. elegans
NP_493666
403
46055
T159
V
L
I
I
L
A
W
T
I
S
F
V
C
A
L
Sea Urchin
Strong. purpuratus
XP_797514
357
41080
I113
T
I
E
R
Y
V
A
I
C
H
P
M
K
A
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
21.8
69.8
N.A.
81.1
27.5
N.A.
27.1
21.4
20
45.2
46.5
23
21.3
25.1
22.9
Protein Similarity:
100
99.5
40.6
79.7
N.A.
87.2
44.8
N.A.
45.2
40.4
40.6
61.5
64.2
44.8
39.5
45.9
41.9
P-Site Identity:
100
100
6.6
66.6
N.A.
60
0
N.A.
6.6
6.6
0
13.3
6.6
0
6.6
0
0
P-Site Similarity:
100
100
33.3
86.6
N.A.
80
13.3
N.A.
20
6.6
13.3
26.6
13.3
6.6
6.6
20
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
14
14
7
0
14
7
7
0
14
7
0
14
14
0
% A
% Cys:
7
0
0
0
34
7
0
0
7
0
0
0
7
0
0
% C
% Asp:
0
7
0
0
0
0
0
7
0
0
0
7
0
7
0
% D
% Glu:
0
0
7
0
0
0
0
0
0
0
0
0
0
27
7
% E
% Phe:
0
0
7
7
0
0
0
20
0
0
14
7
0
7
0
% F
% Gly:
0
34
0
7
7
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
14
0
0
0
14
0
0
0
7
0
27
27
0
7
% H
% Ile:
7
14
14
20
7
7
14
7
14
7
0
0
7
0
0
% I
% Lys:
7
0
7
7
7
0
7
0
14
0
7
0
7
0
7
% K
% Leu:
14
7
27
0
14
7
7
0
14
0
0
20
7
14
7
% L
% Met:
0
7
0
0
7
0
0
7
0
7
0
7
0
7
0
% M
% Asn:
0
0
0
7
0
27
0
0
7
0
0
0
7
0
0
% N
% Pro:
0
7
7
0
0
7
14
7
0
0
7
0
0
7
7
% P
% Gln:
7
0
0
7
0
0
0
0
0
7
7
0
0
0
14
% Q
% Arg:
20
0
0
7
14
0
27
0
20
7
34
7
7
7
14
% R
% Ser:
0
0
0
7
0
7
14
20
20
7
14
14
7
7
7
% S
% Thr:
14
0
14
14
7
0
0
27
0
27
7
7
7
0
14
% T
% Val:
7
0
0
14
0
7
7
0
7
0
0
7
7
0
20
% V
% Trp:
0
0
7
0
0
0
7
0
0
14
0
0
0
0
0
% W
% Tyr:
14
0
0
0
7
7
0
0
0
7
7
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _