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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GPR39
All Species:
15.15
Human Site:
S208
Identified Species:
23.81
UniProt:
O43194
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43194
NP_001499.1
453
51329
S208
Q
P
E
T
S
N
M
S
I
C
T
N
L
S
S
Chimpanzee
Pan troglodytes
XP_515800
453
51339
S208
Q
P
E
T
S
N
M
S
I
C
T
N
L
S
S
Rhesus Macaque
Macaca mulatta
O97666
380
42588
T150
R
V
S
G
A
V
A
T
A
V
L
W
V
L
A
Dog
Lupus familis
XP_853332
465
51886
S208
R
P
E
T
S
N
M
S
I
C
T
N
L
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q5U431
456
51571
S208
E
P
G
N
S
N
M
S
I
C
T
N
L
S
N
Rat
Rattus norvegicus
P20789
424
47036
I193
T
K
K
F
I
S
A
I
W
L
A
S
A
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506365
416
46666
F186
S
R
S
R
T
K
K
F
I
S
G
I
W
L
A
Chicken
Gallus gallus
O93603
395
44679
F164
V
Y
C
M
L
W
F
F
L
L
D
L
N
I
A
Frog
Xenopus laevis
O42574
385
43291
I155
T
K
G
R
A
K
G
I
V
C
S
V
W
G
I
Zebra Danio
Brachydanio rerio
NP_956711
440
49140
A209
V
L
Y
L
L
V
L
A
G
V
A
F
M
C
R
Tiger Blowfish
Takifugu rubipres
NP_001098705
417
46824
T187
V
Q
N
L
T
F
C
T
N
L
R
E
H
W
V
Fruit Fly
Dros. melanogaster
Q8ITC7
477
53986
E223
P
L
D
H
S
R
I
E
E
S
A
F
C
S
M
Honey Bee
Apis mellifera
NP_001091688
581
66278
M227
H
A
F
E
I
S
T
M
L
F
F
V
L
P
M
Nematode Worm
Caenorhab. elegans
NP_493666
403
46055
Q173
L
P
I
A
F
I
V
Q
I
N
K
L
P
L
P
Sea Urchin
Strong. purpuratus
XP_797514
357
41080
R127
K
A
F
I
S
T
S
R
A
I
K
F
I
I
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
21.8
69.8
N.A.
81.1
27.5
N.A.
27.1
21.4
20
45.2
46.5
23
21.3
25.1
22.9
Protein Similarity:
100
99.5
40.6
79.7
N.A.
87.2
44.8
N.A.
45.2
40.4
40.6
61.5
64.2
44.8
39.5
45.9
41.9
P-Site Identity:
100
100
0
93.3
N.A.
73.3
0
N.A.
6.6
0
6.6
0
0
13.3
6.6
13.3
6.6
P-Site Similarity:
100
100
33.3
100
N.A.
86.6
20
N.A.
20
13.3
26.6
20
13.3
26.6
20
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
14
0
7
14
0
14
7
14
0
20
0
7
0
27
% A
% Cys:
0
0
7
0
0
0
7
0
0
34
0
0
7
7
0
% C
% Asp:
0
0
7
0
0
0
0
0
0
0
7
0
0
0
0
% D
% Glu:
7
0
20
7
0
0
0
7
7
0
0
7
0
0
0
% E
% Phe:
0
0
14
7
7
7
7
14
0
7
7
20
0
0
0
% F
% Gly:
0
0
14
7
0
0
7
0
7
0
7
0
0
7
0
% G
% His:
7
0
0
7
0
0
0
0
0
0
0
0
7
0
0
% H
% Ile:
0
0
7
7
14
7
7
14
40
7
0
7
7
14
7
% I
% Lys:
7
14
7
0
0
14
7
0
0
0
14
0
0
0
0
% K
% Leu:
7
14
0
14
14
0
7
0
14
20
7
14
34
27
7
% L
% Met:
0
0
0
7
0
0
27
7
0
0
0
0
7
0
14
% M
% Asn:
0
0
7
7
0
27
0
0
7
7
0
27
7
0
7
% N
% Pro:
7
34
0
0
0
0
0
0
0
0
0
0
7
7
7
% P
% Gln:
14
7
0
0
0
0
0
7
0
0
0
0
0
0
0
% Q
% Arg:
14
7
0
14
0
7
0
7
0
0
7
0
0
0
7
% R
% Ser:
7
0
14
0
40
14
7
27
0
14
7
7
0
34
20
% S
% Thr:
14
0
0
20
14
7
7
14
0
0
27
0
0
0
0
% T
% Val:
20
7
0
0
0
14
7
0
7
14
0
14
7
0
7
% V
% Trp:
0
0
0
0
0
7
0
0
7
0
0
7
14
7
0
% W
% Tyr:
0
7
7
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _