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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GPR39
All Species:
15.15
Human Site:
S274
Identified Species:
23.81
UniProt:
O43194
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43194
NP_001499.1
453
51329
S274
R
K
S
E
S
E
E
S
R
T
A
R
R
Q
T
Chimpanzee
Pan troglodytes
XP_515800
453
51339
S274
R
K
S
E
S
E
E
S
R
T
A
R
R
Q
T
Rhesus Macaque
Macaca mulatta
O97666
380
42588
I216
G
F
V
V
P
F
T
I
M
L
T
C
Y
F
F
Dog
Lupus familis
XP_853332
465
51886
S274
K
K
S
E
S
E
E
S
R
T
S
R
R
Q
I
Cat
Felis silvestris
Mouse
Mus musculus
Q5U431
456
51571
S274
R
K
S
E
S
E
E
S
R
T
A
R
R
Q
T
Rat
Rattus norvegicus
P20789
424
47036
V259
V
I
S
I
L
N
T
V
I
A
N
K
L
T
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506365
416
46666
V252
F
P
M
V
V
I
S
V
L
N
T
I
I
A
N
Chicken
Gallus gallus
O93603
395
44679
K230
N
P
I
P
S
D
P
K
E
N
S
N
T
W
K
Frog
Xenopus laevis
O42574
385
43291
V221
P
L
I
I
M
I
F
V
Y
I
R
V
F
K
E
Zebra Danio
Brachydanio rerio
NP_956711
440
49140
M275
P
N
Q
I
R
R
L
M
T
A
A
V
P
K
S
Tiger Blowfish
Takifugu rubipres
NP_001098705
417
46824
A253
E
S
S
R
V
K
M
A
R
K
Q
T
I
I
F
Fruit Fly
Dros. melanogaster
Q8ITC7
477
53986
S289
N
N
R
E
T
R
N
S
Q
M
R
K
K
T
V
Honey Bee
Apis mellifera
NP_001091688
581
66278
A293
M
L
V
A
V
V
V
A
F
F
I
C
W
A
P
Nematode Worm
Caenorhab. elegans
NP_493666
403
46055
A239
I
A
I
V
I
M
Y
A
H
I
A
V
Q
L
E
Sea Urchin
Strong. purpuratus
XP_797514
357
41080
L193
L
F
L
L
P
M
T
L
I
I
V
L
Y
S
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
21.8
69.8
N.A.
81.1
27.5
N.A.
27.1
21.4
20
45.2
46.5
23
21.3
25.1
22.9
Protein Similarity:
100
99.5
40.6
79.7
N.A.
87.2
44.8
N.A.
45.2
40.4
40.6
61.5
64.2
44.8
39.5
45.9
41.9
P-Site Identity:
100
100
0
80
N.A.
100
6.6
N.A.
0
6.6
0
6.6
13.3
13.3
0
6.6
0
P-Site Similarity:
100
100
0
93.3
N.A.
100
13.3
N.A.
0
20
6.6
20
26.6
40
6.6
20
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
7
0
0
0
20
0
14
34
0
0
14
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
14
0
0
0
% C
% Asp:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% D
% Glu:
7
0
0
34
0
27
27
0
7
0
0
0
0
0
14
% E
% Phe:
7
14
0
0
0
7
7
0
7
7
0
0
7
7
14
% F
% Gly:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% H
% Ile:
7
7
20
20
7
14
0
7
14
20
7
7
14
7
7
% I
% Lys:
7
27
0
0
0
7
0
7
0
7
0
14
7
14
7
% K
% Leu:
7
14
7
7
7
0
7
7
7
7
0
7
7
7
7
% L
% Met:
7
0
7
0
7
14
7
7
7
7
0
0
0
0
0
% M
% Asn:
14
14
0
0
0
7
7
0
0
14
7
7
0
0
7
% N
% Pro:
14
14
0
7
14
0
7
0
0
0
0
0
7
0
7
% P
% Gln:
0
0
7
0
0
0
0
0
7
0
7
0
7
27
0
% Q
% Arg:
20
0
7
7
7
14
0
0
34
0
14
27
27
0
0
% R
% Ser:
0
7
40
0
34
0
7
34
0
0
14
0
0
7
7
% S
% Thr:
0
0
0
0
7
0
20
0
7
27
14
7
7
14
20
% T
% Val:
7
0
14
20
20
7
7
20
0
0
7
20
0
0
14
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
7
7
0
% W
% Tyr:
0
0
0
0
0
0
7
0
7
0
0
0
14
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _