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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GPR39
All Species:
22.73
Human Site:
S348
Identified Species:
35.71
UniProt:
O43194
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43194
NP_001499.1
453
51329
S348
P
L
L
Y
T
V
S
S
Q
Q
F
R
R
V
F
Chimpanzee
Pan troglodytes
XP_515800
453
51339
S348
P
L
L
Y
T
V
S
S
Q
Q
F
R
R
V
F
Rhesus Macaque
Macaca mulatta
O97666
380
42588
C281
G
S
L
L
H
W
P
C
D
F
D
L
F
L
M
Dog
Lupus familis
XP_853332
465
51886
S348
P
L
L
Y
N
V
S
S
Q
Q
F
R
T
A
F
Cat
Felis silvestris
Mouse
Mus musculus
Q5U431
456
51571
S348
P
L
L
Y
N
V
S
S
Q
Q
F
R
K
V
F
Rat
Rattus norvegicus
P20789
424
47036
Y324
F
V
V
C
W
L
P
Y
H
V
R
R
L
M
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506365
416
46666
Y317
F
V
V
C
W
L
P
Y
H
I
R
R
L
M
F
Chicken
Gallus gallus
O93603
395
44679
S295
V
V
V
N
S
F
L
S
S
P
F
Q
E
N
W
Frog
Xenopus laevis
O42574
385
43291
L286
G
T
F
T
L
C
W
L
P
F
F
L
A
N
V
Zebra Danio
Brachydanio rerio
NP_956711
440
49140
R340
L
S
L
Q
H
A
N
R
R
T
L
E
N
S
G
Tiger Blowfish
Takifugu rubipres
NP_001098705
417
46824
F318
L
S
S
V
I
N
P
F
L
Y
N
L
S
S
R
Fruit Fly
Dros. melanogaster
Q8ITC7
477
53986
S360
P
I
V
Y
S
V
M
S
R
R
Y
R
V
A
F
Honey Bee
Apis mellifera
NP_001091688
581
66278
N427
I
S
N
M
T
E
Y
N
G
L
T
E
P
K
K
Nematode Worm
Caenorhab. elegans
NP_493666
403
46055
T304
T
T
W
S
E
T
T
T
I
S
P
P
V
Q
F
Sea Urchin
Strong. purpuratus
XP_797514
357
41080
F258
L
V
V
I
A
A
S
F
F
I
C
W
F
P
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
21.8
69.8
N.A.
81.1
27.5
N.A.
27.1
21.4
20
45.2
46.5
23
21.3
25.1
22.9
Protein Similarity:
100
99.5
40.6
79.7
N.A.
87.2
44.8
N.A.
45.2
40.4
40.6
61.5
64.2
44.8
39.5
45.9
41.9
P-Site Identity:
100
100
6.6
80
N.A.
86.6
13.3
N.A.
13.3
13.3
6.6
6.6
0
40
6.6
6.6
13.3
P-Site Similarity:
100
100
13.3
80
N.A.
93.3
40
N.A.
40
46.6
6.6
20
0
80
13.3
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
7
14
0
0
0
0
0
0
7
14
0
% A
% Cys:
0
0
0
14
0
7
0
7
0
0
7
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
7
0
7
0
0
0
0
% D
% Glu:
0
0
0
0
7
7
0
0
0
0
0
14
7
0
0
% E
% Phe:
14
0
7
0
0
7
0
14
7
14
40
0
14
0
60
% F
% Gly:
14
0
0
0
0
0
0
0
7
0
0
0
0
0
7
% G
% His:
0
0
0
0
14
0
0
0
14
0
0
0
0
0
0
% H
% Ile:
7
7
0
7
7
0
0
0
7
14
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
7
7
7
% K
% Leu:
20
27
40
7
7
14
7
7
7
7
7
20
14
7
0
% L
% Met:
0
0
0
7
0
0
7
0
0
0
0
0
0
14
7
% M
% Asn:
0
0
7
7
14
7
7
7
0
0
7
0
7
14
0
% N
% Pro:
34
0
0
0
0
0
27
0
7
7
7
7
7
7
0
% P
% Gln:
0
0
0
7
0
0
0
0
27
27
0
7
0
7
0
% Q
% Arg:
0
0
0
0
0
0
0
7
14
7
14
47
14
0
7
% R
% Ser:
0
27
7
7
14
0
34
40
7
7
0
0
7
14
0
% S
% Thr:
7
14
0
7
20
7
7
7
0
7
7
0
7
0
0
% T
% Val:
7
27
34
7
0
34
0
0
0
7
0
0
14
20
7
% V
% Trp:
0
0
7
0
14
7
7
0
0
0
0
7
0
0
7
% W
% Tyr:
0
0
0
34
0
0
7
14
0
7
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _