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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GPR39
All Species:
6.67
Human Site:
S396
Identified Species:
10.48
UniProt:
O43194
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43194
NP_001499.1
453
51329
S396
Q
R
P
L
L
F
A
S
R
R
Q
S
S
A
R
Chimpanzee
Pan troglodytes
XP_515800
453
51339
S396
Q
R
P
L
L
F
A
S
R
R
Q
S
S
A
R
Rhesus Macaque
Macaca mulatta
O97666
380
42588
G327
C
T
S
M
L
C
C
G
Q
S
R
C
A
G
T
Dog
Lupus familis
XP_853332
465
51886
A412
A
P
P
T
P
A
P
A
Q
A
T
L
A
C
H
Cat
Felis silvestris
Mouse
Mus musculus
Q5U431
456
51571
R399
L
I
F
L
A
S
R
R
S
N
S
S
S
R
R
Rat
Rattus norvegicus
P20789
424
47036
L371
I
N
P
I
L
Y
N
L
V
S
A
N
F
R
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506365
416
46666
N363
A
I
N
P
I
L
Y
N
L
V
S
A
N
F
R
Chicken
Gallus gallus
O93603
395
44679
K342
K
L
C
N
C
H
L
K
R
D
K
K
P
A
N
Frog
Xenopus laevis
O42574
385
43291
R332
Y
C
R
S
P
D
F
R
K
A
F
K
R
L
L
Zebra Danio
Brachydanio rerio
NP_956711
440
49140
L387
S
A
E
R
R
D
S
L
N
T
T
D
R
P
Q
Tiger Blowfish
Takifugu rubipres
NP_001098705
417
46824
L364
S
R
S
L
R
P
L
L
R
S
L
R
R
N
T
Fruit Fly
Dros. melanogaster
Q8ITC7
477
53986
T416
Q
H
P
N
K
F
E
T
D
S
S
S
A
N
R
Honey Bee
Apis mellifera
NP_001091688
581
66278
I502
P
R
T
L
T
L
G
I
F
A
E
K
L
R
L
Nematode Worm
Caenorhab. elegans
NP_493666
403
46055
I350
R
S
A
F
C
R
T
I
L
G
D
H
I
A
N
Sea Urchin
Strong. purpuratus
XP_797514
357
41080
A304
V
L
L
Y
V
S
S
A
I
N
P
I
L
Y
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
21.8
69.8
N.A.
81.1
27.5
N.A.
27.1
21.4
20
45.2
46.5
23
21.3
25.1
22.9
Protein Similarity:
100
99.5
40.6
79.7
N.A.
87.2
44.8
N.A.
45.2
40.4
40.6
61.5
64.2
44.8
39.5
45.9
41.9
P-Site Identity:
100
100
6.6
6.6
N.A.
26.6
13.3
N.A.
6.6
13.3
0
0
20
33.3
13.3
6.6
0
P-Site Similarity:
100
100
33.3
26.6
N.A.
26.6
40
N.A.
33.3
26.6
6.6
13.3
20
46.6
20
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
7
7
0
7
7
14
14
0
20
7
7
20
27
0
% A
% Cys:
7
7
7
0
14
7
7
0
0
0
0
7
0
7
0
% C
% Asp:
0
0
0
0
0
14
0
0
7
7
7
7
0
0
0
% D
% Glu:
0
0
7
0
0
0
7
0
0
0
7
0
0
0
0
% E
% Phe:
0
0
7
7
0
20
7
0
7
0
7
0
7
7
0
% F
% Gly:
0
0
0
0
0
0
7
7
0
7
0
0
0
7
0
% G
% His:
0
7
0
0
0
7
0
0
0
0
0
7
0
0
7
% H
% Ile:
7
14
0
7
7
0
0
14
7
0
0
7
7
0
0
% I
% Lys:
7
0
0
0
7
0
0
7
7
0
7
20
0
0
0
% K
% Leu:
7
14
7
34
27
14
14
20
14
0
7
7
14
7
14
% L
% Met:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
7
7
14
0
0
7
7
7
14
0
7
7
14
20
% N
% Pro:
7
7
34
7
14
7
7
0
0
0
7
0
7
7
0
% P
% Gln:
20
0
0
0
0
0
0
0
14
0
14
0
0
0
14
% Q
% Arg:
7
27
7
7
14
7
7
14
27
14
7
7
20
20
34
% R
% Ser:
14
7
14
7
0
14
14
14
7
27
20
27
20
0
0
% S
% Thr:
0
7
7
7
7
0
7
7
0
7
14
0
0
0
14
% T
% Val:
7
0
0
0
7
0
0
0
7
7
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
7
0
7
7
0
0
0
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _