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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GPR39
All Species:
16.36
Human Site:
S435
Identified Species:
25.71
UniProt:
O43194
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43194
NP_001499.1
453
51329
S435
L
E
S
L
E
P
N
S
G
A
K
P
A
N
S
Chimpanzee
Pan troglodytes
XP_515800
453
51339
S435
L
E
S
L
E
P
N
S
G
A
K
P
A
N
S
Rhesus Macaque
Macaca mulatta
O97666
380
42588
H366
G
K
G
G
E
Q
M
H
E
K
S
I
P
Y
S
Dog
Lupus familis
XP_853332
465
51886
S451
L
R
A
D
D
L
D
S
G
D
R
L
G
V
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q5U431
456
51571
S438
P
E
S
P
Q
T
G
S
E
T
K
P
A
G
S
Rat
Rattus norvegicus
P20789
424
47036
S410
R
K
P
N
S
M
S
S
N
H
A
F
S
T
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506365
416
46666
S402
G
K
S
N
S
I
S
S
N
H
T
F
S
S
N
Chicken
Gallus gallus
O93603
395
44679
S381
V
T
N
T
Y
L
S
S
A
K
T
S
I
G
D
Frog
Xenopus laevis
O42574
385
43291
L371
N
S
L
D
T
N
A
L
G
M
C
S
E
C
N
Zebra Danio
Brachydanio rerio
NP_956711
440
49140
N426
D
S
Q
E
K
E
R
N
Q
L
T
H
C
P
T
Tiger Blowfish
Takifugu rubipres
NP_001098705
417
46824
K403
L
S
K
M
E
E
S
K
T
T
L
Q
T
A
D
Fruit Fly
Dros. melanogaster
Q8ITC7
477
53986
S455
I
V
I
V
L
E
N
S
H
T
V
C
E
E
P
Honey Bee
Apis mellifera
NP_001091688
581
66278
H541
L
P
S
R
F
Q
S
H
P
S
I
D
S
A
N
Nematode Worm
Caenorhab. elegans
NP_493666
403
46055
V389
T
L
M
T
R
G
S
V
R
V
D
K
P
H
R
Sea Urchin
Strong. purpuratus
XP_797514
357
41080
S343
S
M
A
T
R
G
H
S
T
Y
I
T
R
T
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
21.8
69.8
N.A.
81.1
27.5
N.A.
27.1
21.4
20
45.2
46.5
23
21.3
25.1
22.9
Protein Similarity:
100
99.5
40.6
79.7
N.A.
87.2
44.8
N.A.
45.2
40.4
40.6
61.5
64.2
44.8
39.5
45.9
41.9
P-Site Identity:
100
100
13.3
20
N.A.
46.6
13.3
N.A.
13.3
6.6
6.6
0
13.3
13.3
13.3
0
13.3
P-Site Similarity:
100
100
20
46.6
N.A.
53.3
33.3
N.A.
46.6
26.6
13.3
20
26.6
26.6
40
13.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
14
0
0
0
7
0
7
14
7
0
20
14
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
7
7
7
7
0
% C
% Asp:
7
0
0
14
7
0
7
0
0
7
7
7
0
0
14
% D
% Glu:
0
20
0
7
27
20
0
0
14
0
0
0
14
7
0
% E
% Phe:
0
0
0
0
7
0
0
0
0
0
0
14
0
0
0
% F
% Gly:
14
0
7
7
0
14
7
0
27
0
0
0
7
14
0
% G
% His:
0
0
0
0
0
0
7
14
7
14
0
7
0
7
0
% H
% Ile:
7
0
7
0
0
7
0
0
0
0
14
7
7
0
0
% I
% Lys:
0
20
7
0
7
0
0
7
0
14
20
7
0
0
0
% K
% Leu:
34
7
7
14
7
14
0
7
0
7
7
7
0
0
0
% L
% Met:
0
7
7
7
0
7
7
0
0
7
0
0
0
0
0
% M
% Asn:
7
0
7
14
0
7
20
7
14
0
0
0
0
14
20
% N
% Pro:
7
7
7
7
0
14
0
0
7
0
0
20
14
7
7
% P
% Gln:
0
0
7
0
7
14
0
0
7
0
0
7
0
0
7
% Q
% Arg:
7
7
0
7
14
0
7
0
7
0
7
0
7
0
7
% R
% Ser:
7
20
34
0
14
0
40
60
0
7
7
14
20
7
40
% S
% Thr:
7
7
0
20
7
7
0
0
14
20
20
7
7
14
7
% T
% Val:
7
7
0
7
0
0
0
7
0
7
7
0
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
7
0
0
0
0
7
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _