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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GPR39
All Species:
9.09
Human Site:
T204
Identified Species:
14.29
UniProt:
O43194
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43194
NP_001499.1
453
51329
T204
R
H
H
E
Q
P
E
T
S
N
M
S
I
C
T
Chimpanzee
Pan troglodytes
XP_515800
453
51339
T204
R
H
H
E
Q
P
E
T
S
N
M
S
I
C
T
Rhesus Macaque
Macaca mulatta
O97666
380
42588
G146
R
L
R
L
R
V
S
G
A
V
A
T
A
V
L
Dog
Lupus familis
XP_853332
465
51886
T204
R
H
H
E
R
P
E
T
S
N
M
S
I
C
T
Cat
Felis silvestris
Mouse
Mus musculus
Q5U431
456
51571
N204
R
H
H
D
E
P
G
N
S
N
M
S
I
C
T
Rat
Rattus norvegicus
P20789
424
47036
F189
S
R
S
R
T
K
K
F
I
S
A
I
W
L
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506365
416
46666
R182
K
S
V
M
S
R
S
R
T
K
K
F
I
S
G
Chicken
Gallus gallus
O93603
395
44679
M160
S
F
A
S
V
Y
C
M
L
W
F
F
L
L
D
Frog
Xenopus laevis
O42574
385
43291
R151
Q
S
L
L
T
K
G
R
A
K
G
I
V
C
S
Zebra Danio
Brachydanio rerio
NP_956711
440
49140
L205
F
T
A
F
V
L
Y
L
L
V
L
A
G
V
A
Tiger Blowfish
Takifugu rubipres
NP_001098705
417
46824
L183
A
D
T
P
V
Q
N
L
T
F
C
T
N
L
R
Fruit Fly
Dros. melanogaster
Q8ITC7
477
53986
H219
Y
L
N
Y
P
L
D
H
S
R
I
E
E
S
A
Honey Bee
Apis mellifera
NP_001091688
581
66278
E223
T
L
I
E
H
A
F
E
I
S
T
M
L
F
F
Nematode Worm
Caenorhab. elegans
NP_493666
403
46055
A169
F
V
C
A
L
P
I
A
F
I
V
Q
I
N
K
Sea Urchin
Strong. purpuratus
XP_797514
357
41080
I123
P
M
K
A
K
A
F
I
S
T
S
R
A
I
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
21.8
69.8
N.A.
81.1
27.5
N.A.
27.1
21.4
20
45.2
46.5
23
21.3
25.1
22.9
Protein Similarity:
100
99.5
40.6
79.7
N.A.
87.2
44.8
N.A.
45.2
40.4
40.6
61.5
64.2
44.8
39.5
45.9
41.9
P-Site Identity:
100
100
6.6
93.3
N.A.
73.3
0
N.A.
6.6
0
6.6
0
0
6.6
6.6
13.3
6.6
P-Site Similarity:
100
100
26.6
100
N.A.
86.6
13.3
N.A.
20
6.6
33.3
13.3
13.3
26.6
20
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
14
14
0
14
0
7
14
0
14
7
14
0
20
% A
% Cys:
0
0
7
0
0
0
7
0
0
0
7
0
0
34
0
% C
% Asp:
0
7
0
7
0
0
7
0
0
0
0
0
0
0
7
% D
% Glu:
0
0
0
27
7
0
20
7
0
0
0
7
7
0
0
% E
% Phe:
14
7
0
7
0
0
14
7
7
7
7
14
0
7
7
% F
% Gly:
0
0
0
0
0
0
14
7
0
0
7
0
7
0
7
% G
% His:
0
27
27
0
7
0
0
7
0
0
0
0
0
0
0
% H
% Ile:
0
0
7
0
0
0
7
7
14
7
7
14
40
7
0
% I
% Lys:
7
0
7
0
7
14
7
0
0
14
7
0
0
0
14
% K
% Leu:
0
20
7
14
7
14
0
14
14
0
7
0
14
20
7
% L
% Met:
0
7
0
7
0
0
0
7
0
0
27
7
0
0
0
% M
% Asn:
0
0
7
0
0
0
7
7
0
27
0
0
7
7
0
% N
% Pro:
7
0
0
7
7
34
0
0
0
0
0
0
0
0
0
% P
% Gln:
7
0
0
0
14
7
0
0
0
0
0
7
0
0
0
% Q
% Arg:
34
7
7
7
14
7
0
14
0
7
0
7
0
0
7
% R
% Ser:
14
14
7
7
7
0
14
0
40
14
7
27
0
14
7
% S
% Thr:
7
7
7
0
14
0
0
20
14
7
7
14
0
0
27
% T
% Val:
0
7
7
0
20
7
0
0
0
14
7
0
7
14
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
7
0
0
7
0
0
% W
% Tyr:
7
0
0
7
0
7
7
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _