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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GPR39
All Species:
9.09
Human Site:
T381
Identified Species:
14.29
UniProt:
O43194
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43194
NP_001499.1
453
51329
T381
L
R
V
H
A
H
S
T
T
D
S
A
R
F
V
Chimpanzee
Pan troglodytes
XP_515800
453
51339
T381
L
R
V
H
A
H
S
T
T
D
S
A
R
F
V
Rhesus Macaque
Macaca mulatta
O97666
380
42588
F312
N
P
F
L
Y
A
F
F
D
P
R
F
R
Q
A
Dog
Lupus familis
XP_853332
465
51886
A397
R
G
V
N
V
Q
D
A
T
G
L
E
A
D
V
Cat
Felis silvestris
Mouse
Mus musculus
Q5U431
456
51571
S384
R
F
I
S
T
K
D
S
T
S
S
A
R
S
P
Rat
Rattus norvegicus
P20789
424
47036
A356
Y
F
Y
M
L
T
N
A
L
F
Y
V
S
S
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506365
416
46666
N348
H
Y
F
Y
M
L
T
N
V
L
F
Y
V
S
S
Chicken
Gallus gallus
O93603
395
44679
Q327
V
I
Y
N
L
M
S
Q
K
F
R
A
A
F
R
Frog
Xenopus laevis
O42574
385
43291
N317
L
N
W
L
G
Y
A
N
S
A
F
N
P
I
I
Zebra Danio
Brachydanio rerio
NP_956711
440
49140
S372
N
R
I
R
M
A
T
S
S
R
S
T
P
P
S
Tiger Blowfish
Takifugu rubipres
NP_001098705
417
46824
V349
Q
H
V
N
K
R
T
V
P
A
A
A
H
V
T
Fruit Fly
Dros. melanogaster
Q8ITC7
477
53986
H401
S
S
A
Y
D
R
V
H
S
V
H
V
R
A
S
Honey Bee
Apis mellifera
NP_001091688
581
66278
C487
A
A
T
Y
M
N
E
C
L
L
N
I
Q
K
S
Nematode Worm
Caenorhab. elegans
NP_493666
403
46055
Y335
S
A
A
N
P
I
L
Y
N
I
L
S
Q
K
Y
Sea Urchin
Strong. purpuratus
XP_797514
357
41080
R289
P
V
Q
E
I
Y
Y
R
G
L
Y
H
F
S
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
21.8
69.8
N.A.
81.1
27.5
N.A.
27.1
21.4
20
45.2
46.5
23
21.3
25.1
22.9
Protein Similarity:
100
99.5
40.6
79.7
N.A.
87.2
44.8
N.A.
45.2
40.4
40.6
61.5
64.2
44.8
39.5
45.9
41.9
P-Site Identity:
100
100
6.6
20
N.A.
26.6
0
N.A.
0
20
6.6
13.3
13.3
6.6
0
0
0
P-Site Similarity:
100
100
6.6
26.6
N.A.
40
6.6
N.A.
13.3
33.3
33.3
40
33.3
20
26.6
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
14
14
0
14
14
7
14
0
14
7
34
14
7
14
% A
% Cys:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
7
0
14
0
7
14
0
0
0
7
0
% D
% Glu:
0
0
0
7
0
0
7
0
0
0
0
7
0
0
0
% E
% Phe:
0
14
14
0
0
0
7
7
0
14
14
7
7
20
0
% F
% Gly:
0
7
0
0
7
0
0
0
7
7
0
0
0
0
0
% G
% His:
7
7
0
14
0
14
0
7
0
0
7
7
7
0
0
% H
% Ile:
0
7
14
0
7
7
0
0
0
7
0
7
0
7
14
% I
% Lys:
0
0
0
0
7
7
0
0
7
0
0
0
0
14
0
% K
% Leu:
20
0
0
14
14
7
7
0
14
20
14
0
0
0
0
% L
% Met:
0
0
0
7
20
7
0
0
0
0
0
0
0
0
0
% M
% Asn:
14
7
0
27
0
7
7
14
7
0
7
7
0
0
0
% N
% Pro:
7
7
0
0
7
0
0
0
7
7
0
0
14
7
7
% P
% Gln:
7
0
7
0
0
7
0
7
0
0
0
0
14
7
0
% Q
% Arg:
14
20
0
7
0
14
0
7
0
7
14
0
34
0
7
% R
% Ser:
14
7
0
7
0
0
20
14
20
7
27
7
7
27
27
% S
% Thr:
0
0
7
0
7
7
20
14
27
0
0
7
0
0
7
% T
% Val:
7
7
27
0
7
0
7
7
7
7
0
14
7
7
20
% V
% Trp:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
7
14
20
7
14
7
7
0
0
14
7
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _