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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GPR39
All Species:
8.18
Human Site:
T405
Identified Species:
12.86
UniProt:
O43194
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43194
NP_001499.1
453
51329
T405
R
Q
S
S
A
R
R
T
E
K
I
F
L
S
T
Chimpanzee
Pan troglodytes
XP_515800
453
51339
T405
R
Q
S
S
A
R
R
T
E
K
V
F
L
S
T
Rhesus Macaque
Macaca mulatta
O97666
380
42588
H336
S
R
C
A
G
T
S
H
S
S
S
G
E
K
S
Dog
Lupus familis
XP_853332
465
51886
G421
A
T
L
A
C
H
G
G
D
N
T
L
C
L
G
Cat
Felis silvestris
Mouse
Mus musculus
Q5U431
456
51571
N408
N
S
S
S
R
R
T
N
K
V
F
L
S
T
F
Rat
Rattus norvegicus
P20789
424
47036
F380
S
A
N
F
R
Q
V
F
L
S
T
L
A
C
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506365
416
46666
I372
V
S
A
N
F
R
Q
I
F
V
S
T
L
A
F
Chicken
Gallus gallus
O93603
395
44679
S351
D
K
K
P
A
N
Y
S
V
A
L
N
Y
N
V
Frog
Xenopus laevis
O42574
385
43291
C341
A
F
K
R
L
L
C
C
P
K
K
A
D
R
H
Zebra Danio
Brachydanio rerio
NP_956711
440
49140
E396
T
T
D
R
P
Q
G
E
G
K
L
T
L
D
P
Tiger Blowfish
Takifugu rubipres
NP_001098705
417
46824
M373
S
L
R
R
N
T
D
M
R
S
N
K
A
E
E
Fruit Fly
Dros. melanogaster
Q8ITC7
477
53986
L425
S
S
S
A
N
R
V
L
I
K
K
T
Y
S
L
Honey Bee
Apis mellifera
NP_001091688
581
66278
T511
A
E
K
L
R
L
E
T
K
E
L
F
S
S
Q
Nematode Worm
Caenorhab. elegans
NP_493666
403
46055
V359
G
D
H
I
A
N
F
V
F
K
G
H
Q
R
P
Sea Urchin
Strong. purpuratus
XP_797514
357
41080
M313
N
P
I
L
Y
N
V
M
S
A
R
F
R
R
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
21.8
69.8
N.A.
81.1
27.5
N.A.
27.1
21.4
20
45.2
46.5
23
21.3
25.1
22.9
Protein Similarity:
100
99.5
40.6
79.7
N.A.
87.2
44.8
N.A.
45.2
40.4
40.6
61.5
64.2
44.8
39.5
45.9
41.9
P-Site Identity:
100
93.3
0
0
N.A.
20
0
N.A.
13.3
6.6
6.6
13.3
0
26.6
20
13.3
6.6
P-Site Similarity:
100
100
20
13.3
N.A.
33.3
13.3
N.A.
40
33.3
6.6
26.6
0
33.3
46.6
13.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
7
7
20
27
0
0
0
0
14
0
7
14
7
7
% A
% Cys:
0
0
7
0
7
0
7
7
0
0
0
0
7
7
0
% C
% Asp:
7
7
7
0
0
0
7
0
7
0
0
0
7
7
0
% D
% Glu:
0
7
0
0
0
0
7
7
14
7
0
0
7
7
7
% E
% Phe:
0
7
0
7
7
0
7
7
14
0
7
27
0
0
14
% F
% Gly:
7
0
0
0
7
0
14
7
7
0
7
7
0
0
7
% G
% His:
0
0
7
0
0
7
0
7
0
0
0
7
0
0
7
% H
% Ile:
0
0
7
7
0
0
0
7
7
0
7
0
0
0
0
% I
% Lys:
0
7
20
0
0
0
0
0
14
40
14
7
0
7
0
% K
% Leu:
0
7
7
14
7
14
0
7
7
0
20
20
27
7
14
% L
% Met:
0
0
0
0
0
0
0
14
0
0
0
0
0
0
0
% M
% Asn:
14
0
7
7
14
20
0
7
0
7
7
7
0
7
0
% N
% Pro:
0
7
0
7
7
0
0
0
7
0
0
0
0
0
14
% P
% Gln:
0
14
0
0
0
14
7
0
0
0
0
0
7
0
7
% Q
% Arg:
14
7
7
20
20
34
14
0
7
0
7
0
7
20
0
% R
% Ser:
27
20
27
20
0
0
7
7
14
20
14
0
14
27
7
% S
% Thr:
7
14
0
0
0
14
7
20
0
0
14
20
0
7
14
% T
% Val:
7
0
0
0
0
0
20
7
7
14
7
0
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
7
0
7
0
0
0
0
0
14
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _