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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEPT4
All Species:
13.64
Human Site:
T295
Identified Species:
30
UniProt:
O43236
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43236
NP_004565.1
478
55098
T295
L
A
K
A
D
T
L
T
P
P
E
V
D
H
K
Chimpanzee
Pan troglodytes
Q5R1W1
434
50272
T280
N
G
E
H
C
D
F
T
I
L
R
N
M
L
I
Rhesus Macaque
Macaca mulatta
XP_001104631
578
65159
T395
L
A
K
A
D
T
L
T
P
P
E
V
D
R
K
Dog
Lupus familis
XP_537693
331
38609
D177
V
Y
Q
F
P
D
C
D
S
D
E
D
E
D
F
Cat
Felis silvestris
Mouse
Mus musculus
P28661
478
54917
T295
L
A
K
A
D
T
L
T
P
P
E
V
D
R
K
Rat
Rattus norvegicus
Q9JJM9
369
42834
I215
E
E
I
D
K
F
G
I
H
V
Y
Q
F
P
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509185
527
59238
T344
L
A
K
A
D
T
L
T
P
P
E
V
E
H
K
Chicken
Gallus gallus
Q5ZMH1
349
40206
K195
L
K
E
R
E
R
L
K
R
R
V
L
D
E
I
Frog
Xenopus laevis
Q63ZQ1
352
40432
V198
R
E
R
L
K
R
R
V
L
D
E
I
E
E
R
Zebra Danio
Brachydanio rerio
A2BGU8
361
40623
H207
L
D
I
E
F
M
K
H
L
S
R
V
V
N
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P42207
361
41113
K207
E
I
E
S
H
G
I
K
I
Y
P
L
P
D
C
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
44.7
80.4
67.3
N.A.
92.6
60
N.A.
69
47.2
47
37.2
N.A.
47.4
N.A.
N.A.
N.A.
Protein Similarity:
100
59.4
80.8
68.4
N.A.
95.1
68.1
N.A.
76
59.8
59
52.9
N.A.
60.8
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
93.3
6.6
N.A.
93.3
0
N.A.
93.3
20
6.6
13.3
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
93.3
26.6
N.A.
93.3
6.6
N.A.
100
40
33.3
20
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
37
0
37
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
10
0
10
0
0
0
0
0
0
0
10
% C
% Asp:
0
10
0
10
37
19
0
10
0
19
0
10
37
19
0
% D
% Glu:
19
19
28
10
10
0
0
0
0
0
55
0
28
19
10
% E
% Phe:
0
0
0
10
10
10
10
0
0
0
0
0
10
0
10
% F
% Gly:
0
10
0
0
0
10
10
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
10
10
0
0
10
10
0
0
0
0
19
0
% H
% Ile:
0
10
19
0
0
0
10
10
19
0
0
10
0
0
28
% I
% Lys:
0
10
37
0
19
0
10
19
0
0
0
0
0
0
37
% K
% Leu:
55
0
0
10
0
0
46
0
19
10
0
19
0
10
0
% L
% Met:
0
0
0
0
0
10
0
0
0
0
0
0
10
0
0
% M
% Asn:
10
0
0
0
0
0
0
0
0
0
0
10
0
10
0
% N
% Pro:
0
0
0
0
10
0
0
0
37
37
10
0
10
10
0
% P
% Gln:
0
0
10
0
0
0
0
0
0
0
0
10
0
0
0
% Q
% Arg:
10
0
10
10
0
19
10
0
10
10
19
0
0
19
10
% R
% Ser:
0
0
0
10
0
0
0
0
10
10
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
37
0
46
0
0
0
0
0
0
0
% T
% Val:
10
0
0
0
0
0
0
10
0
10
10
46
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
0
0
0
10
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _